Veterinarska stanica, Vol. 48 No. 5, 2017.
Izvorni znanstveni članak
Impact of Giardia duodenalis infection on haematological and biochemical parameters in dogs
Iva Šmit
; Veterinarski fakultet Sveučilišta u Zagrebu, Hrvatska
Dalibor Potočnjak
; Veterinarski fakultet Sveučilišta u Zagrebu, Hrvatska
Vesna Matijatko
; Veterinarski fakultet Sveučilišta u Zagrebu, Hrvatska
Ines Jović
; Veterinarski fakultet Sveučilišta u Zagrebu, Hrvatska
Filip Kajin
; Veterinarski fakultet Sveučilišta u Zagrebu, Hrvatska
Mirna Brkljačić
; Veterinarski fakultet Sveučilišta u Zagrebu, Hrvatska
Relja Beck
; Hrvatski veterinarski institut, Zagreb, Hrvatska
Sažetak
In small animal practice, chronic digestive disorders are the most commonly reported disorders. The most common chronic digestive symptom is diarrhoea, which may be caused by a large number of digestive disorders (bacterial, viral, fungal or protozoan infection), inflammatory bowel disease, intoxication, or can be food
induced. In this study, we retrospectively collected data from 82 dogs of both sexes, regardless of breed, older than one year and fully vaccinated, that were presented to the Clinic for Internal Diseases of the Faculty of Veterinary Medicine, University of Zagreb. Dogs were presented to the clinic for a variety of reasons, including gastrointestinal symptoms, routine examination or general health examination. Diagnostic tests were performed, including CBC and serum biochemical analysis, to exclude underlying disorders and to evaluate potential changes in laboratory findings. All faecal samples were examined for intestinal parasites by direct microscopic examination after the flotation technique and by immunofluorescence, and giardia positive samples were subjected to further genetic characterization by using PCR of small subunit ribosomal DNA (Ssu rRNA gene) genes. Blood was collected from the venae cephalicae antebrachii for haematology and biochemistry analysis as a part of the routine examination. Haematology results and most biochemistry results showed no statistically significant differences between dogs with or without G. duodenalis infections.Statistically significant differences were found in Giardia positive dogs for
the concentrations of BUN and activity of lipase, CPK and ALT. Haematology results and most biochemistry results showed no statistically significant differences between dogs infected with different strains of G. duodenalis (C or D). A statistically significant increase in amylase activity was found in dogs infected with G. duodenalis assemblage C and a statistically significant decrease in CPK activity was found in dogs infected with G. duodenalis assemblage D. The results of this study contradict some of traditionally accepted “knowledge” in small animal practice in Croatia, such as the expectation of eosinophilia in dogs infected with gastrointestinal parasites. A lack of eosinophilia should not be an argument for exclusion of parasite invasions in dogs, especially G. duodenalis invasion.
Ključne riječi
G. duodenalis; dog; hematological and biochemical parameters
Hrčak ID:
222639
URI
Datum izdavanja:
15.10.2017.
Posjeta: 1.658 *