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https://doi.org/10.15255/CABEQ.2019.1656

Nonsteroidal Anti-Inflammatory Drug Solid-State Microencapsulation on Green Activated Carbon – Mass Transfer and Host-Guest Interactions

Z. Lyubenova Yaneva orcid id orcid.org/0000-0001-8159-4530 ; Chemistry Unit, Department of Pharmacology, Animal Physiology and Physiological Chemistry, Faculty of Veterinary Medicine, Trakia University, Students Campus, 6000 Stara Zagora, Bulgaria


Puni tekst: engleski pdf 3.268 Kb

str. 249-269

preuzimanja: 339

citiraj


Sažetak

The present study investigated the drug-carrier capacity of green activated carbon derived from fruit stones by steam-gas activation (ACSTA) towards the nonsteroidal anti-inflammatory drug (NSAID) ibuprofen (IBU), and assessed the host-guest interactions and mass transfer mechanism/s of the drug microencapsulation and in vitro release processes. The mass transfer studies outlined that the process of IBU encapsulation on ACSTA microparticles was predominantly controlled by intraparticle solid phase diffusion.







This work is licensed under a Creative Commons Attribution 4.0 International License.

Ključne riječi

microencapsulation; ibuprofen; activated carbon; in vitro release

Hrčak ID:

223897

URI

https://hrcak.srce.hr/223897

Datum izdavanja:

31.7.2019.

Posjeta: 885 *