Expression of the Renin-Angiotensin System Components in Oncologic Diseases
Sergey Dolomatov
; Department of Medical Biology, Medical Academy SI Georgievsky, Crimea Federal University, Simferopol, Russian Federation jurisdiction
Walery Zukow
orcid.org/0000-0002-7675-6117
; Faculty of Earth, Nicolaus Copernicus University, Toruń, Poland
Nikolay Novikov
; A. Tsyb Medical Radiological Research Center, branch of the National Medical Research Radiological Center of the Ministry of Health of the Russian Federation, Obninsk, Kaluga Region, Russian Federation
Alexandra Markaryan
; Department of Medical Biology, Medical Academy SI Georgievsky, Crimea Federal University, Simferopol, Russian Federation jurisdiction
Elena Eremeeva
; Department of Medical Biology, Medical Academy SI Georgievsky, Crimea Federal University, Simferopol, Russian Federation jurisdiction
APA 6th Edition Dolomatov, S., Zukow, W., Novikov, N., Markaryan, A. i Eremeeva, E. (2019). Expression of the Renin-Angiotensin System Components in Oncologic Diseases. Acta clinica Croatica, 58. (2.), 354-363. https://doi.org/10.20471/acc.2019.58.02.21
MLA 8th Edition Dolomatov, Sergey, et al. "Expression of the Renin-Angiotensin System Components in Oncologic Diseases." Acta clinica Croatica, vol. 58., br. 2., 2019, str. 354-363. https://doi.org/10.20471/acc.2019.58.02.21. Citirano 18.01.2021.
Chicago 17th Edition Dolomatov, Sergey, Walery Zukow, Nikolay Novikov, Alexandra Markaryan i Elena Eremeeva. "Expression of the Renin-Angiotensin System Components in Oncologic Diseases." Acta clinica Croatica 58., br. 2. (2019): 354-363. https://doi.org/10.20471/acc.2019.58.02.21
Harvard Dolomatov, S., et al. (2019). 'Expression of the Renin-Angiotensin System Components in Oncologic Diseases', Acta clinica Croatica, 58.(2.), str. 354-363. https://doi.org/10.20471/acc.2019.58.02.21
Vancouver Dolomatov S, Zukow W, Novikov N, Markaryan A, Eremeeva E. Expression of the Renin-Angiotensin System Components in Oncologic Diseases. Acta clinica Croatica [Internet]. 2019 [pristupljeno 18.01.2021.];58.(2.):354-363. https://doi.org/10.20471/acc.2019.58.02.21
IEEE S. Dolomatov, W. Zukow, N. Novikov, A. Markaryan i E. Eremeeva, "Expression of the Renin-Angiotensin System Components in Oncologic Diseases", Acta clinica Croatica, vol.58., br. 2., str. 354-363, 2019. [Online]. https://doi.org/10.20471/acc.2019.58.02.21
Sažetak The literature devoted to changes in the expression of the renin-angiotensin system (RAS) proteins of cancer cells was analyzed. The dynamics of RAS protein expression in malignant tumors and the possible role of epigenetic mechanisms in these processes are briefly reviewed. Through research of the epigenetic mechanisms in cancer, principally new techniques for their correction based on the use of selective regulatory systems of covalent modification of histone proteins (for example, deacetylase inhibitor) and microRNA synthesis technologies have been developed. Literature data show promising pharmacological correction of epigenetic modification of chromatin in the treatment of cancer.