Pregledni rad

CANNABIS IN CANCER PAIN MANAGEMENT

MIRJANA LONČARIĆ–KATUŠIN ; Opća bolnica Karlovac, Odjel za anesteziologiju, reanimatologiju i intenzivnu medicinu, Karlovac, Hrvatska
DAHNA ARBANAS ; Karlovačke ljekarne, Karlovac, Hrvatska
ANTONIO ŽILIĆ ; Opća bolnica Karlovac, Odjel za anesteziologiju, reanimatologiju i intenzivnu medicinu, Karlovac, Hrvatska
ERVIN JANČIĆ ; Opća bolnica Karlovac, Odjel za neurologiju, Karlovac, Hrvatska
JOSIP ŽUNIĆ ; Opća bolnica Karlovac, Odjel za anesteziologiju, reanimatologiju i intenzivnu medicinu, Karlovac, Hrvatska

Sažetak

Cannabinoids, the active components of Cannabis sativa, mimic the effects of endogenous cannabinoids (endocannabinoids), activating specifi c cannabinoid receptors, particularly CB1 found predominantly in the central nervous system and CB2 found predominantly in the cells involved in immune function. Cannabinoids are effective in the treatment of pain in adults, chemotherapy-induced nausea and vomiting and spasticity associated with multiple sclerosis. In cancer patients, cannabis has a number of potential benefi ts, especially in the management of symptoms. Medical cannabis reduces chronic or neuropathic pain in advanced cancer patients. Insuffi cient management of cancer-associated chronic and neuropathic pain adversely affects patient quality of life. In neuropathic pain and cancer pain, medical cannabinoids should only be considered for patients whose conditions are refractory to standard therapies. Medical cannabinoids are adjuncts to other prescribed analgesics. The potential harms and benefi ts should be discussed with the patient.

Ključne riječi

medical cannabis; cancer; pain

Hrčak ID:

224659

URI

https://hrcak.srce.hr/224659

Datum izdavanja:

14.7.2019.

Podaci na drugim jezicima: hrvatski

Posjeta: 1.492 *