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Kratko priopćenje
https://doi.org/10.18054/pb.v120i2-3.6749

The effect of subminimal inhibitory concentrations of antibiotics on the adherence ability of Pseudomonas aeruginosa to epithelial cells in vitro

Sanja Bekić ; Sanja Bekić, MD, MSc, Family Medicine Practice, Osijek, Croatia; Department of Internal Medicine, Family Medicine and History of Medicine, Faculty of Medicine, University of Osijek, Osijek, Croatia
Domagoj Drenjančević ; Department of Transfusion Medicine, Osijek University Hospital, Osijek, Croatia; Department of Microbiology and Parasitology, Faculty of Medicine, University of Osijek, Osijek, Croatia
Jasminka Talapko ; Department of Microbiology and Parasitology, Faculty of Medicine, University of Osijek, Osijek, Croatia; Faculty of Dental Medicine and Health, University of Osijek, Osijek, Croatia
Ivan Kotris ; Department of Internal Medicine, General County Hospital Vukovar, Vukovar, Croatia
Ivana Škrlec   ORCID icon orcid.org/0000-0003-1842-930X ; Faculty of Dental Medicine and Health Osijek
Jasmina Vraneš   ORCID icon orcid.org/0000-0002-3282-0973 ; Department of Microbiology and Parasitology, School of Medicine, University of Zagreb, Zagreb, Croatia; Department of Microbiology, Andrija Stampar Teaching Institute of Public Health, Zagreb, Croatia

Puni tekst: engleski, PDF (159 KB) str. 119-124 preuzimanja: 240* citiraj
APA 6th Edition
Bekić, S., Drenjančević, D., Talapko, J., Kotris, I., Škrlec, I. i Vraneš, J. (2018). The effect of subminimal inhibitory concentrations of antibiotics on the adherence ability of Pseudomonas aeruginosa to epithelial cells in vitro. Periodicum biologorum, 120 (2-3), 119-124. https://doi.org/10.18054/pb.v120i2-3.6749
MLA 8th Edition
Bekić, Sanja, et al. "The effect of subminimal inhibitory concentrations of antibiotics on the adherence ability of Pseudomonas aeruginosa to epithelial cells in vitro." Periodicum biologorum, vol. 120, br. 2-3, 2018, str. 119-124. https://doi.org/10.18054/pb.v120i2-3.6749. Citirano 28.11.2020.
Chicago 17th Edition
Bekić, Sanja, Domagoj Drenjančević, Jasminka Talapko, Ivan Kotris, Ivana Škrlec i Jasmina Vraneš. "The effect of subminimal inhibitory concentrations of antibiotics on the adherence ability of Pseudomonas aeruginosa to epithelial cells in vitro." Periodicum biologorum 120, br. 2-3 (2018): 119-124. https://doi.org/10.18054/pb.v120i2-3.6749
Harvard
Bekić, S., et al. (2018). 'The effect of subminimal inhibitory concentrations of antibiotics on the adherence ability of Pseudomonas aeruginosa to epithelial cells in vitro', Periodicum biologorum, 120(2-3), str. 119-124. https://doi.org/10.18054/pb.v120i2-3.6749
Vancouver
Bekić S, Drenjančević D, Talapko J, Kotris I, Škrlec I, Vraneš J. The effect of subminimal inhibitory concentrations of antibiotics on the adherence ability of Pseudomonas aeruginosa to epithelial cells in vitro. Periodicum biologorum [Internet]. 2018 [pristupljeno 28.11.2020.];120(2-3):119-124. https://doi.org/10.18054/pb.v120i2-3.6749
IEEE
S. Bekić, D. Drenjančević, J. Talapko, I. Kotris, I. Škrlec i J. Vraneš, "The effect of subminimal inhibitory concentrations of antibiotics on the adherence ability of Pseudomonas aeruginosa to epithelial cells in vitro", Periodicum biologorum, vol.120, br. 2-3, str. 119-124, 2018. [Online]. https://doi.org/10.18054/pb.v120i2-3.6749

Sažetak

Background and purpose: The aim of this study was to examine the influence of subminimal inhibitory concentrations (subMICs) of ceftazidime, ciprofloxacin and gentamicin on the adherence ability and morphology of wild-type Pseudomonas aeruginosa strains to the Buffalo green monkey kidney cell line, using indirect immunofluorescence staining.


Materials and methods: Bacterial adherence changes were tested before and after exposure to 1/2, 1/4, 1/8, 1/16 and 1/32 MIC of antibiotics.


Results: A statistical difference in the number of attached bacteria after exposure to all subMICs of ceftazidime and ciprofloxacin was observed (p<0.05), even after only 1/2 MIC of gentamicin.


Conclusion: The results of this study have shown that antibiotics in much lower concentrations than those necessary for inhibition of bacterial multiplications could damage the adherence of Pseudomonas aeruginosa to the epithelial cell line.

Ključne riječi
Ceftazidime; Ciprofloxacin; Gentamicin; Bacterial adherence

Hrčak ID: 225311

URI
https://hrcak.srce.hr/225311

Posjeta: 377 *