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https://doi.org/10.5562/cca3536

Organocatalytic Synthesis of α,α–Diaryl Substituted α–Amino Acid Derivatives by an Interrupted Three-Component Ugi Reaction

Danijel Glavač ; Division of Organic Chemistry and Biochemistry, Ruđer Bošković Institute, Bijenička c. 54, HR-10000 Zagreb, Croatia
Ivanka Jerić ; Division of Organic Chemistry and Biochemistry, Ruđer Bošković Institute, Bijenička c. 54, HR-10000 Zagreb, Croatia
Matija Gredičak ; Division of Organic Chemistry and Biochemistry, Ruđer Bošković Institute, Bijenička c. 54, HR-10000 Zagreb, Croatia

Puni tekst: engleski, pdf (1 MB) str. 203-209 preuzimanja: 201* citiraj
APA 6th Edition
Glavač, D., Jerić, I. i Gredičak, M. (2019). Organocatalytic Synthesis of α,α–Diaryl Substituted α–Amino Acid Derivatives by an Interrupted Three-Component Ugi Reaction. Croatica Chemica Acta, 92 (2), 203-209. https://doi.org/10.5562/cca3536
MLA 8th Edition
Glavač, Danijel, et al. "Organocatalytic Synthesis of α,α–Diaryl Substituted α–Amino Acid Derivatives by an Interrupted Three-Component Ugi Reaction." Croatica Chemica Acta, vol. 92, br. 2, 2019, str. 203-209. https://doi.org/10.5562/cca3536. Citirano 27.02.2021.
Chicago 17th Edition
Glavač, Danijel, Ivanka Jerić i Matija Gredičak. "Organocatalytic Synthesis of α,α–Diaryl Substituted α–Amino Acid Derivatives by an Interrupted Three-Component Ugi Reaction." Croatica Chemica Acta 92, br. 2 (2019): 203-209. https://doi.org/10.5562/cca3536
Harvard
Glavač, D., Jerić, I., i Gredičak, M. (2019). 'Organocatalytic Synthesis of α,α–Diaryl Substituted α–Amino Acid Derivatives by an Interrupted Three-Component Ugi Reaction', Croatica Chemica Acta, 92(2), str. 203-209. https://doi.org/10.5562/cca3536
Vancouver
Glavač D, Jerić I, Gredičak M. Organocatalytic Synthesis of α,α–Diaryl Substituted α–Amino Acid Derivatives by an Interrupted Three-Component Ugi Reaction. Croatica Chemica Acta [Internet]. 2019 [pristupljeno 27.02.2021.];92(2):203-209. https://doi.org/10.5562/cca3536
IEEE
D. Glavač, I. Jerić i M. Gredičak, "Organocatalytic Synthesis of α,α–Diaryl Substituted α–Amino Acid Derivatives by an Interrupted Three-Component Ugi Reaction", Croatica Chemica Acta, vol.92, br. 2, str. 203-209, 2019. [Online]. https://doi.org/10.5562/cca3536

Sažetak
An organocatalytic interrupted three-component Ugi reaction for the synthesis of α,α–diaryl α–amino acid derivatives is described. The transformation proceeds with a range of isocyanides and 3-aryl isoindolinone alcohols using Brønsted acid catalysts to afford products in good to excellent yields. Based on the obtained results, a reaction mechanism is proposed and discussed.

Creative Commons License This work is licensed under a Creative Commons Attribution 4.0 International License.

Ključne riječi
organocatalytic synthesis; α,α–disubstituted amino acids; Ugi reaction

Hrčak ID: 226909

URI
https://hrcak.srce.hr/226909

Posjeta: 417 *