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Professional paper

Clinicopathological characteristic and prognostic factors for FIGO stage 1A2-1B2 of cervical cancer

Daren Lučinger ; University of Zagreb, School of medicine
Luka Matak ; General hospital Zadar, Department of obstetrics and gynecology
Mislav Mikuš ; Department of obstetrics and gynecology UHC Zagreb
Ante Ćorušić ; Department of obstetrics and gynecology UHC Zagreb
Pavao Planinić ; Department of obstetrics and gynecology UHC Zagreb
Goran Vujić ; Department of Obstetrics and Gynecology UHC Zagreb

Fulltext: english, pdf (618 KB) pages 65-69 downloads: 59* cite
APA 6th Edition
Lučinger, D., Matak, L., Mikuš, M., Ćorušić, A., Planinić, P. & Vujić, G. (2020). Clinicopathological characteristic and prognostic factors for FIGO stage 1A2-1B2 of cervical cancer. Medica Jadertina, 50 (1), 65-69. Retrieved from https://hrcak.srce.hr/236692
MLA 8th Edition
Lučinger, Daren, et al. "Clinicopathological characteristic and prognostic factors for FIGO stage 1A2-1B2 of cervical cancer." Medica Jadertina, vol. 50, no. 1, 2020, pp. 65-69. https://hrcak.srce.hr/236692. Accessed 18 Jan. 2021.
Chicago 17th Edition
Lučinger, Daren, Luka Matak, Mislav Mikuš, Ante Ćorušić, Pavao Planinić and Goran Vujić. "Clinicopathological characteristic and prognostic factors for FIGO stage 1A2-1B2 of cervical cancer." Medica Jadertina 50, no. 1 (2020): 65-69. https://hrcak.srce.hr/236692
Harvard
Lučinger, D., et al. (2020). 'Clinicopathological characteristic and prognostic factors for FIGO stage 1A2-1B2 of cervical cancer', Medica Jadertina, 50(1), pp. 65-69. Available at: https://hrcak.srce.hr/236692 (Accessed 18 January 2021)
Vancouver
Lučinger D, Matak L, Mikuš M, Ćorušić A, Planinić P, Vujić G. Clinicopathological characteristic and prognostic factors for FIGO stage 1A2-1B2 of cervical cancer. Medica Jadertina [Internet]. 2020 [cited 2021 January 18];50(1):65-69. Available from: https://hrcak.srce.hr/236692
IEEE
D. Lučinger, L. Matak, M. Mikuš, A. Ćorušić, P. Planinić and G. Vujić, "Clinicopathological characteristic and prognostic factors for FIGO stage 1A2-1B2 of cervical cancer", Medica Jadertina, vol.50, no. 1, pp. 65-69, 2020. [Online]. Available: https://hrcak.srce.hr/236692. [Accessed: 18 January 2021]

Abstracts
Introduction: Cervical cancer is one of the most common malignant tumors of the female reproductive system in women between 15-35 years of age. It takes third place in the frequency of all reproductive system cancers in Croatia. The aim of the present study was to analyze prognostic factors influencing on reccurence to improve therapeutic management.
Materials and Methods: We reviewed medical records and pathological materials obtained from 61 patients with stage IA2-IB2 between 2003 and 2013. The comparison of women with and without recurrence showed statistical significance in certain factors; age when diagnosed, size of tumor, depth of stromal invasion, lymph vascular space invasion, infiltration of the uterine isthmus and lymph node metastases.
Results: Median age at diagnosis was 46 years. Lymph-vascular space invasion (LVSI) was present in 22 (36.1%) with cervical isthmus involvement in 18 (29.5%) patients. Tumor recurrence within observation interval was present in 6 (9.8%) patients. Median time of reccurrence was 24 (range 14-48) months. In univariate statistical analysis lymph-vascular space invasion (P=0.011), cervical isthmus involvement (P=0.002) and positive lymph nodes (P=0.005) were significant parameters for occurrence of recidive while in multivariate statistical analysis cervical isthmus involvement (P=0.036) remained as only independent risk factor for recidive occurrence.
Conclusion: Cervical isthmus involvement could be of prognostic importance especially in the early stage of cervical cancer when we might decide in adding radiotherapy and concomitant chemotherapy to improve overall survival and lower recurrence rate.

Keywords
cervical cancer; prognostic factors; recurrence rate

Hrčak ID: 236692

URI
https://hrcak.srce.hr/236692

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