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Stručni rad
https://doi.org/10.20471/LO.2020.48.01.03

Histopatološke karakteristike raka dojke od 2005 do 2019 u jednom centru u Hrvatskoj: pregled promjena nakon uvođenja mammografskog probira

Snježana Ramić   ORCID icon orcid.org/0000-0002-5916-8815 ; Department of Oncological Pathology and Clinical Cytology, 'Ljudevit Jurak' University Department of Pathology, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Melita Perić-Balja ; Department of Oncological Pathology and Clinical Cytology, 'Ljudevit Jurak' University Department of Pathology, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Vesna Ramljak ; Department of Oncological Pathology and Clinical Cytology, 'Ljudevit Jurak' University Department of Pathology, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Sara Zadro ; Department of Surgical Oncology, University Hospital for Tumors, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Iva Kirac ; Department of Surgical Oncology, University Hospital for Tumors, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Tomislav Orešić ; Department of Reconstructive Surgery, University Hospital for Tumors, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
Ivan Milas ; Department of Reconstructive Surgery, University Hospital for Tumors, Sestre milosrdnice University Hospital Center, Zagreb, Croatia

Puni tekst: engleski, pdf (617 KB) str. 13-19 preuzimanja: 91* citiraj
APA 6th Edition
Ramić, S., Perić-Balja, M., Ramljak, V., Zadro, S., Kirac, I., Orešić, T. i Milas, I. (2020). Histopathological features of breast cancer from 2005 to 2019 in a single center in Croatia: an overview of changes following the introduction of mammography screening. Libri Oncologici, 48 (1), 13-19. https://doi.org/10.20471/LO.2020.48.01.03
MLA 8th Edition
Ramić, Snježana, et al. "Histopathological features of breast cancer from 2005 to 2019 in a single center in Croatia: an overview of changes following the introduction of mammography screening." Libri Oncologici, vol. 48, br. 1, 2020, str. 13-19. https://doi.org/10.20471/LO.2020.48.01.03. Citirano 09.05.2021.
Chicago 17th Edition
Ramić, Snježana, Melita Perić-Balja, Vesna Ramljak, Sara Zadro, Iva Kirac, Tomislav Orešić i Ivan Milas. "Histopathological features of breast cancer from 2005 to 2019 in a single center in Croatia: an overview of changes following the introduction of mammography screening." Libri Oncologici 48, br. 1 (2020): 13-19. https://doi.org/10.20471/LO.2020.48.01.03
Harvard
Ramić, S., et al. (2020). 'Histopathological features of breast cancer from 2005 to 2019 in a single center in Croatia: an overview of changes following the introduction of mammography screening', Libri Oncologici, 48(1), str. 13-19. https://doi.org/10.20471/LO.2020.48.01.03
Vancouver
Ramić S, Perić-Balja M, Ramljak V, Zadro S, Kirac I, Orešić T i sur. Histopathological features of breast cancer from 2005 to 2019 in a single center in Croatia: an overview of changes following the introduction of mammography screening. Libri Oncologici [Internet]. 2020 [pristupljeno 09.05.2021.];48(1):13-19. https://doi.org/10.20471/LO.2020.48.01.03
IEEE
S. Ramić, et al., "Histopathological features of breast cancer from 2005 to 2019 in a single center in Croatia: an overview of changes following the introduction of mammography screening", Libri Oncologici, vol.48, br. 1, str. 13-19, 2020. [Online]. https://doi.org/10.20471/LO.2020.48.01.03

Sažetak
UVOD: Nacionalni program za mamografski probir raka dojke u Hrvatskoj započeo je 2006, s ciljem otkrivanja raka u ranijem stadiju bolesti. Program uključuje mamografski pregled žena u dobi od 50 do 69. Cilj našeg istraživanja je utvrditi razlike u patohistološkim karakteristikama raka dojke prije uvođenja probira s novodijagnosticiranim.
MATERIJALI I METODE: Retrospektivno smo u jednom centru prikupili podatke o patohistološkim karakteristikama raka dojke bolesnica oboljelih na početku mamografskog probira (2005-2007; N=1833) i podatke o novooboljelima iz razdoblja više od deset godina nakon uvedenog probira (2017-2019; N=2676). Dobivene podatke analizirali smo upotrebom χ2 testa.
REZULTATI: Zbrinuli smo 31.5% više novodijagnosticiranih bolesnica s karcinomom dojke. Naši rezultati nisu pokazali statistički značajne razlike u veličini tumora, histološkom gradusu ili pozitivnom status limfnih čvorova u podpazušnoj jami u skupini novodijagnosticiranih bolesnica s karcinomom dojke u usporedbi s onima iz razdoblja prije mamografskog probira. Prosječna dob oboljevanja je 61 godina s prosječnom veličinom tumora od 22 mm (medijan 18 mm), u oba razdoblja. Oko 45 % bolesnica je dijagnosticirano s pT1N0, u oba razdoblja.
ZAKLJUČAK: U razdoblju nakon uvođenja probira zbrinuli smo 32% više oboljelih od raka dojke u našoj instituciji. Nismo zabilježili razlike u patohistološkim karakteristikama tumora, niti u prosječnoj veličini tumora između ova dva perioda.

Ključne riječi
rak dojke; patohistološke karakteristike; mamografski probir

Hrčak ID: 240532

URI
https://hrcak.srce.hr/240532

[engleski]

Posjeta: 283 *