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https://doi.org/10.15255/CABEQ.2020.1783

From Bio-waste to Bone Substitute: Synthesis of Biomimetic Hydroxyapatite and Its Use in Chitosan-based Composite Scaffold Preparation

A. Ressler   ORCID icon orcid.org/0000-0003-2178-5188 ; Faculty of Chemical Engineering and Technology, University of Zagreb, HR-10001 Zagreb, Marulićev trg 19, p.p.177, Croatia
A. Gudelj ; Faculty of Chemical Engineering and Technology, University of Zagreb, HR-10001 Zagreb, Marulićev trg 19, p.p.177, Croatia
K. Zadro ; Faculty of Chemical Engineering and Technology, University of Zagreb, HR-10001 Zagreb, Marulićev trg 19, p.p.177, Croatia
M. Antunović   ORCID icon orcid.org/0000-0002-8233-0059 ; Faculty of Chemical Engineering and Technology, University of Zagreb, HR-10001 Zagreb, Marulićev trg 19, p.p.177, Croatia
M. Cvetnić   ORCID icon orcid.org/0000-0002-0168-8092 ; Faculty of Chemical Engineering and Technology, University of Zagreb, HR-10001 Zagreb, Marulićev trg 19, p.p.177, Croatia
M. Ivanković   ORCID icon orcid.org/0000-0002-3796-8344 ; Faculty of Chemical Engineering and Technology, University of Zagreb, HR-10001 Zagreb, Marulićev trg 19, p.p.177, Croatia
H. Ivanković ; Faculty of Chemical Engineering and Technology, University of Zagreb, HR-10001 Zagreb, Marulićev trg 19, p.p.177, Croatia

Puni tekst: engleski, pdf (3 MB) str. 59-71 preuzimanja: 29* citiraj
APA 6th Edition
Ressler, A., Gudelj, A., Zadro, K., Antunović, M., Cvetnić, M., Ivanković, M. i Ivanković, H. (2020). From Bio-waste to Bone Substitute: Synthesis of Biomimetic Hydroxyapatite and Its Use in Chitosan-based Composite Scaffold Preparation. Chemical and Biochemical Engineering Quarterly, 34 (2), 59-71. https://doi.org/10.15255/CABEQ.2020.1783
MLA 8th Edition
Ressler, A., et al. "From Bio-waste to Bone Substitute: Synthesis of Biomimetic Hydroxyapatite and Its Use in Chitosan-based Composite Scaffold Preparation." Chemical and Biochemical Engineering Quarterly, vol. 34, br. 2, 2020, str. 59-71. https://doi.org/10.15255/CABEQ.2020.1783. Citirano 28.09.2020.
Chicago 17th Edition
Ressler, A., A. Gudelj, K. Zadro, M. Antunović, M. Cvetnić, M. Ivanković i H. Ivanković. "From Bio-waste to Bone Substitute: Synthesis of Biomimetic Hydroxyapatite and Its Use in Chitosan-based Composite Scaffold Preparation." Chemical and Biochemical Engineering Quarterly 34, br. 2 (2020): 59-71. https://doi.org/10.15255/CABEQ.2020.1783
Harvard
Ressler, A., et al. (2020). 'From Bio-waste to Bone Substitute: Synthesis of Biomimetic Hydroxyapatite and Its Use in Chitosan-based Composite Scaffold Preparation', Chemical and Biochemical Engineering Quarterly, 34(2), str. 59-71. https://doi.org/10.15255/CABEQ.2020.1783
Vancouver
Ressler A, Gudelj A, Zadro K, Antunović M, Cvetnić M, Ivanković M i sur. From Bio-waste to Bone Substitute: Synthesis of Biomimetic Hydroxyapatite and Its Use in Chitosan-based Composite Scaffold Preparation. Chemical and Biochemical Engineering Quarterly [Internet]. 2020 [pristupljeno 28.09.2020.];34(2):59-71. https://doi.org/10.15255/CABEQ.2020.1783
IEEE
A. Ressler, et al., "From Bio-waste to Bone Substitute: Synthesis of Biomimetic Hydroxyapatite and Its Use in Chitosan-based Composite Scaffold Preparation", Chemical and Biochemical Engineering Quarterly, vol.34, br. 2, str. 59-71, 2020. [Online]. https://doi.org/10.15255/CABEQ.2020.1783

Sažetak
Nanocomposite structure of the bone can be mimicked by chitosan/hydroxyapatite (CS/HAp) composite scaffold. Biological hydroxyapatite (HAp) contains various ions, which have a crucial role in bone growth. The aim of the present work was to synthesize biomimetic hydroxyapatite and prepare composite scaffolds based on chitosan, where HAp was synthesised from hen eggshells, seashells and cuttlefish bone. The powders were composed of nano-structured calcium deficient HAp and amorphous calcium phosphate (ACP). In the as-prepared powders, Sr2+, Mg2+ and Na+ ions were detected as a result of using biogenic precursor of Ca2+ ions. Highly porous CS/HAp structures have
been prepared by freeze-gelation technique. The CS/HAp scaffolds have shown highly porous structure with very well interconnected pores and homogeneously dispersed HAp particles. The MTT assay of CS/HAp scaffolds has shown no toxicity, and the live/dead assay has confirmed good viability and proliferation of seeded cells.






Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.

Ključne riječi
biogenic source; chitosan; hydroxyapatite; scaffold; trace element

Hrčak ID: 241912

URI
https://hrcak.srce.hr/241912

Posjeta: 57 *