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Emerging considerations in the reversal of neuromuscular blockade and residual block

WAYNE T. NICHOLSON ; Mayo Clinic College of Medicine, Mary Brigh 2-752, 200 First Street SW, Rochester, Minnesota 55905, USA
JURAJ SPRUNG ; Mayo Clinic College of Medicine, Mary Brigh 2-752, 200 First Street SW, Rochester, Minnesota 55905, USA
CHRISTOPHER J. JANKOWSKI ; Mayo Clinic College of Medicine, Mary Brigh 2-752, 200 First Street SW, Rochester, Minnesota 55905, USA

Puni tekst: engleski, pdf (88 KB) str. 35-38 preuzimanja: 1.446* citiraj
APA 6th Edition
NICHOLSON, W.T., SPRUNG, J. i JANKOWSKI, C.J. (2008). Emerging considerations in the reversal of neuromuscular blockade and residual block. Signa vitae, 3 (1), 35-38. Preuzeto s https://hrcak.srce.hr/22525
MLA 8th Edition
NICHOLSON, WAYNE T., et al. "Emerging considerations in the reversal of neuromuscular blockade and residual block." Signa vitae, vol. 3, br. 1, 2008, str. 35-38. https://hrcak.srce.hr/22525. Citirano 01.04.2020.
Chicago 17th Edition
NICHOLSON, WAYNE T., JURAJ SPRUNG i CHRISTOPHER J. JANKOWSKI. "Emerging considerations in the reversal of neuromuscular blockade and residual block." Signa vitae 3, br. 1 (2008): 35-38. https://hrcak.srce.hr/22525
Harvard
NICHOLSON, W.T., SPRUNG, J., i JANKOWSKI, C.J. (2008). 'Emerging considerations in the reversal of neuromuscular blockade and residual block', Signa vitae, 3(1), str. 35-38. Preuzeto s: https://hrcak.srce.hr/22525 (Datum pristupa: 01.04.2020.)
Vancouver
NICHOLSON WT, SPRUNG J, JANKOWSKI CJ. Emerging considerations in the reversal of neuromuscular blockade and residual block. Signa vitae [Internet]. 2008 [pristupljeno 01.04.2020.];3(1):35-38. Dostupno na: https://hrcak.srce.hr/22525
IEEE
W.T. NICHOLSON, J. SPRUNG i C.J. JANKOWSKI, "Emerging considerations in the reversal of neuromuscular blockade and residual block", Signa vitae, vol.3, br. 1, str. 35-38, 2008. [Online]. Dostupno na: https://hrcak.srce.hr/22525. [Citirano: 01.04.2020.]

Sažetak
Incomplete recovery following reversal of neuromuscular blockade can present as a clinical problem in surgical patients. Emerging pharmacologic solutions may prevent such adverse outcomes in the future. We briefly review two methods of pharmacologic reversal of neuromuscular blockade. Both methods of reversal are effective. However the early studies of the new compound, sugammadex has been shown to achieve a more rapid, stable reversal of steroidal based neuromuscular blocking agents compared to neostigmine. Due to the novel mechanism of action of this agent, sugammadex has been demonstrated to be effective even when administered during profound neuromuscular block, without evidence of recurarization.

Ključne riječi
sugammadex; Org 25969; cyclodextrin; rocuronium; cholinesterase inhibitor

Hrčak ID: 22525

URI
https://hrcak.srce.hr/22525

Posjeta: 1.665 *