Ostalo
Retinal Branch Vein Occlusion by Arterial Wall Plaque in Hereditary Amyloidosis
Davor Galetović
Lovro Bojić
Kajo Bućan
Dobrila Karlica
Ljubo Znaor
Sažetak
We report on ocular finding that was the first sign of hereditary amyloidosis. This case report describes a 34-year-old man with a sudden loss of visual acuity, positive family history, and systemic manifestations of amyloidosis that included peripheral neuropathy, restrictive cardiomyopathy and amyloid deposits detected in colon biopsy specimen. The main outcome measures were visual acuity, fundus photography and fluorescein angiography (FA). In the early stage of hereditary amyloidosis, fundus photography of the right eye demonstrated subretinal macular hemorrhage, retinal hemorrhages and staining in the lower temporal branch wall of the central retinal artery. FA showed vascular occlusion and focal staining of the artery, and in the late-stage fluorescein leakage of the inframacular branch vein. The site of "leakage" was treated with laser photocoagulation. After 3 weeks fundus photography showed that subretinal and retinal hemorrhages were mainly reabsorbed, but focal staining of the lower temporal artery wall was still present, and new focal staining of the upper temporal artery wall appeared. FA showed two vascular occlusions, with focal staining of arterial walls, and in late stage the sites of hyperfluorescence revealed that these vascular changes continued to progress. Focal retinal arterial amyloid deposits may be a rare ocular finding of hereditary amyloidosis, causing clinical finding of vein branch occlusion.
Ključne riječi
Retinal vein occlusion; Arterial wall deposits; Amyloidosis
Hrčak ID:
22771
URI
Datum izdavanja:
1.4.2008.
Posjeta: 1.857 *