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Vascular Thrombosis Associated with Antiphospholipide Syndrome

Marija Glasnović
Ivica Bošnjak
Aleksandar Včev
Ivan Soldo
Dražen Bedeković
Sabina Milaković
Valentina Hečimović
Elizabeta Horvatić
Mijo Bardek

Sažetak

The aim of this study was to present our diagnostic and therapeutic experience with antiphospholipide syndrome
(APS) and vascular thrombosis. Ninety-nine patients with positive antiphospholipide antibodies (aPL) and vascular
thrombosis were included in the study: forty patients, according to clinical classification criteria, had primary antiphospholipide
syndrome (PAPS), and fifty-nine patients had secondary antiphospholipide syndrome (SAPS). In PAPS group,
82.5% of the patients were LA-positive, 37.5% of the patients were IgG aCL-positive, 27.5% of the patients were IgM
aCL-positive, and 15% of the patients were IgG antib2GPI-positive. In SAPS group, 61% of the patients were LA-positive,
50.8% of the patients were IgG aCL-positive, and 47.5% of the patients were IgM aCL-positive. Administered therapy
was low molecular weight heparin (LMWH) throughout 7 days, followed by warfarin with prothrombin time maintained
between 2.0 and 3.0 INR.

Ključne riječi

antiphospholipid syndrome; vascular thrombosis; antibodies

Hrčak ID:

22821

URI

https://hrcak.srce.hr/22821

Datum izdavanja:

8.5.2008.

Posjeta: 1.191 *