Izvorni znanstveni članak
Serum Immunoglobulins IgG, IgA and IgM in Patients with Oral Lichen Ruber
Dolores Biočina-Lukenda
Ana Cekić-Arambašin
Jasenka Markeljević
Dino Buković
Sažetak
The aim of this study was to determine level of serum IgA, IgG and IgM in patients with OLR as indicators of
humoral immunity which might reflect cell-mediated immunity. This study was conducted on 30 patients (age 60.17±
11.75) with clinically and histopathologically confirmed diagnosis of OLR and 30 healthy controls (age 56.16±11.82)
Determination of serum IgA, IgG and IgM was performed by use of standard laser nephelometry in both patients and
controls. Statistical analysis was done using Mann-Whitney U test and the level of significance was determined as p values
lower than 0.05. Serum IgA and IgM in patients with OLR were significantly increased in comparison to the control
group, while serum IgG levels were higher in patients with OLR but they did not reach significance. We might conclude
that elevated levels of serum IgA and IgM show that humoral immunity is implicated in the pathogenesis of OLR.
Ključne riječi
serum immunoglobulin A; G; M; oral lichen ruber
Hrčak ID:
22831
URI
Datum izdavanja:
8.5.2008.
Posjeta: 964 *