Skoči na glavni sadržaj

Acta clinica Croatica, Vol. 59. No. Supplement 1, 2020.

Pregledni rad

https://doi.org/10.20471/acc.2020.59.s1.08

Risk Factors for Thyroid Cancer: What Do We Know So Far?

Tatjana Bogović Crnčić orcid id orcid.org/0000-0003-4152-7928 ; Department of Nuclear Medicine, University of Rijeka Faculty of Medicine, Clinical Department of Nuclear Medicine, Rijeka Clinical Hospital Centre, Rijeka, Croatia
Maja Ilić Tomaš orcid id orcid.org/0000-0001-5863-9251 ; Department of Nuclear Medicine, University of Rijeka Faculty of Medicine, Clinical Department of Nuclear Medicine, Rijeka Clinical Hospital Centre, Rijeka, Croatia
Neva Girotto orcid id orcid.org/0000-0001-5445-3310 ; Department of Nuclear Medicine, University of Rijeka Faculty of Medicine, Clinical Department of Nuclear Medicine, Rijeka Clinical Hospital Centre, Rijeka, Croatia
Svjetlana Grbac Ivanković orcid id orcid.org/0000-0002-4958-6183 ; Department of Nuclear Medicine, University of Rijeka Faculty of Medicine, Clinical Department of Nuclear Medicine, Rijeka Clinical Hospital Centre, Rijeka, Croatia

Puni tekst: engleski pdf 254 Kb

str. 66-72

preuzimanja: 572

citiraj

Sažetak

Thyroid cancer (TC) is the most common endocrine cancer today. The rising incidence
of the differentiated papillary type cannot be entirely explained by early and meticulous diagnosis,
since a proportion of large tumors has also been reported. In this review, we present the results
of numerous investigations focused on possible factors causing increased TC incidence, such as chromosomal
and genetic alterations, iodine intake, TSH level, autoimmune thyroid disease, gender, estrogen,
obesity, lifestyle changes, and environmental pollutants. Up to now, only childhood exposure to
ionizing radiation has been fully recognized as a risk factor. There is also a possibility that yet undiscovered
carcinogens, especially during intrauterine life or early childhood, might be responsible for
increased TC incidence as well as epigenetic changes. Therefore, more studies are necessary in order to
further investigate the potential risk factors for TC and their mechanisms of action.

Ključne riječi

radiation exposure; risk factors; thyroid cancer

Hrčak ID:

247901

URI

https://hrcak.srce.hr/247901

Datum izdavanja:

1.11.2020.

Podaci na drugim jezicima: hrvatski

Posjeta: 2.581 *