Croatica Chemica Acta, Vol. 27 No. 4, 1955.
Izvorni znanstveni članak
The Reduction of Some Phthalamic Acids with Lithium Aluminum Hydride
D. E. Sunko
; Chemical Laboratory, Department of Physiology, Medical Faculty, University of Zagreb and Department of Biochemistry, Institute »Ruder Boskovic«, Zagreb, Croatia, Yugoslavia
Sažetak
The phthalamic acids II and VII derived from 2-phthalimidooctadecane (I) and (-)-2-phthalimido-3-octadecanone (VI) were submitted to reduction with lithium aluminum hydride. The reduction of II afforded two products, i. e. 2-(o-hydroxymethylbenzamido)-octadecane (III) and 2-(o-hydroxymethylbenzylamino)-octadecane(IV). By reduction of VII only 2-(o-hydroxymethylbenzamido)-3-octadecanol (VIII) was obtained. When hydrolyzed III and VIII yielded, after subsequent acylation, 2-acetamidooctadecane (V) and 2-benzami do-3-hydroxyoctadecane (IX), respectively. The hydrogenolysis of IV afforded V. These reactions may present an alternative method for the elimination of the phthaloyl group.
Ključne riječi
Hrčak ID:
247903
URI
Datum izdavanja:
1.2.1956.
Posjeta: 280 *