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Acta Pharmaceutica, Vol. 58 No. 3, 2008.

Kratko priopćenje
https://doi.org/10.2478/v10007-008-00011-6

2-Amino-5-sulfanil-1,3,4-tidiazoli: Nova serija selektivnih inhibitora ciklooksigenaze-2

RAJESH SHARMA
JITENDRA SAINY
SUBHASH CHANDRA CHATURVEDI

Puni tekst: engleski, pdf (106 KB) str. 317-326 preuzimanja: 989* citiraj
APA 6th Edition
SHARMA, R., SAINY, J. i CHATURVEDI, S.C. (2008). 2-Amino-5-sulfanyl-1,3,4-thidiazoles: A new series of selective cyclooxygenase-2 inhibitors. Acta Pharmaceutica, 58 (3), 317-326. https://doi.org/10.2478/v10007-008-00011-6
MLA 8th Edition
SHARMA, RAJESH, et al. "2-Amino-5-sulfanyl-1,3,4-thidiazoles: A new series of selective cyclooxygenase-2 inhibitors." Acta Pharmaceutica, vol. 58, br. 3, 2008, str. 317-326. https://doi.org/10.2478/v10007-008-00011-6. Citirano 24.02.2019.
Chicago 17th Edition
SHARMA, RAJESH, JITENDRA SAINY i SUBHASH CHANDRA CHATURVEDI. "2-Amino-5-sulfanyl-1,3,4-thidiazoles: A new series of selective cyclooxygenase-2 inhibitors." Acta Pharmaceutica 58, br. 3 (2008): 317-326. https://doi.org/10.2478/v10007-008-00011-6
Harvard
SHARMA, R., SAINY, J., i CHATURVEDI, S.C. (2008). '2-Amino-5-sulfanyl-1,3,4-thidiazoles: A new series of selective cyclooxygenase-2 inhibitors', Acta Pharmaceutica, 58(3), str. 317-326. doi: https://doi.org/10.2478/v10007-008-00011-6
Vancouver
SHARMA R, SAINY J, CHATURVEDI SC. 2-Amino-5-sulfanyl-1,3,4-thidiazoles: A new series of selective cyclooxygenase-2 inhibitors. Acta Pharm. [Internet]. 2008 [pristupljeno 24.02.2019.];58(3):317-326. doi: https://doi.org/10.2478/v10007-008-00011-6
IEEE
R. SHARMA, J. SAINY i S.C. CHATURVEDI, "2-Amino-5-sulfanyl-1,3,4-thidiazoles: A new series of selective cyclooxygenase-2 inhibitors", Acta Pharmaceutica, vol.58, br. 3, str. 317-326, 2008. [Online]. doi: https://doi.org/10.2478/v10007-008-00011-6

Sažetak
Sintetizirana je nova serija inhibitora ciklooksigenaze-2 s 2-amino-5-sulfanil-1,3,4-tiadiazolom. Novi spojevi karakterizirani su uobičajenim analitičkim i spektroskopskim metodama. Sintetiziranim spojevima ispitana je sposobnost inhibicije ciklooksigenaze kolorimetrijskim COX testom (goveđi COX), protuupalno djelovanje na edem šape induciran karageninom i analgetsko djelovanje metodom pomicanja repa. Neki spojevi su pokazali značajno biološko djelovanje.

Ključne riječi
2-amino-5-sulfanil-1,3,4-tiadiazoli; ciklooksigenaza-1; ciklooksigenaza -2, protuupalno djelovanje; analgetsko djelovanje

Hrčak ID: 22932

URI
https://hrcak.srce.hr/22932

[engleski]

Posjeta: 1.264 *