hrcak mascot   Srce   HID

Acta Pharmaceutica, Vol. 58 No. 3, 2008.

Kratko priopćenje
https://doi.org/10.2478/v10007-008-00011-6

2-Amino-5-sulfanyl-1,3,4-thidiazoles: A new series of selective cyclooxygenase-2 inhibitors

RAJESH SHARMA
JITENDRA SAINY
SUBHASH CHANDRA CHATURVEDI

Puni tekst: engleski, pdf (106 KB) str. 317-326 preuzimanja: 996* citiraj
APA 6th Edition
SHARMA, R., SAINY, J. i CHATURVEDI, S.C. (2008). 2-Amino-5-sulfanyl-1,3,4-thidiazoles: A new series of selective cyclooxygenase-2 inhibitors. Acta Pharmaceutica, 58 (3), 317-326. https://doi.org/10.2478/v10007-008-00011-6
MLA 8th Edition
SHARMA, RAJESH, et al. "2-Amino-5-sulfanyl-1,3,4-thidiazoles: A new series of selective cyclooxygenase-2 inhibitors." Acta Pharmaceutica, vol. 58, br. 3, 2008, str. 317-326. https://doi.org/10.2478/v10007-008-00011-6. Citirano 27.05.2019.
Chicago 17th Edition
SHARMA, RAJESH, JITENDRA SAINY i SUBHASH CHANDRA CHATURVEDI. "2-Amino-5-sulfanyl-1,3,4-thidiazoles: A new series of selective cyclooxygenase-2 inhibitors." Acta Pharmaceutica 58, br. 3 (2008): 317-326. https://doi.org/10.2478/v10007-008-00011-6
Harvard
SHARMA, R., SAINY, J., i CHATURVEDI, S.C. (2008). '2-Amino-5-sulfanyl-1,3,4-thidiazoles: A new series of selective cyclooxygenase-2 inhibitors', Acta Pharmaceutica, 58(3), str. 317-326. doi: https://doi.org/10.2478/v10007-008-00011-6
Vancouver
SHARMA R, SAINY J, CHATURVEDI SC. 2-Amino-5-sulfanyl-1,3,4-thidiazoles: A new series of selective cyclooxygenase-2 inhibitors. Acta Pharm. [Internet]. 2008 [pristupljeno 27.05.2019.];58(3):317-326. doi: https://doi.org/10.2478/v10007-008-00011-6
IEEE
R. SHARMA, J. SAINY i S.C. CHATURVEDI, "2-Amino-5-sulfanyl-1,3,4-thidiazoles: A new series of selective cyclooxygenase-2 inhibitors", Acta Pharmaceutica, vol.58, br. 3, str. 317-326, 2008. [Online]. doi: https://doi.org/10.2478/v10007-008-00011-6

Sažetak
A new series of cyclooxygenase-2 inhibitors with 2-amino-5-sulfanyl-1,3,4-thiadiazole as the central scaffold unit has been synthesized. The newly synthesized compounds were characterized by analytical and spectral methods. Compounds were screened for cyclooxygenase inhibitory activity by colorimetric COX (ovine) inhibitor screening assay, anti-inflammatory activity by the carrageenean induced rat paw oedema test and analgesic activity by the tail flick method. Some compounds exhibited significant biological activity.

Ključne riječi
2-amino-5-sulfanyl-1,3,4-thiadiazoles, cyclooxygenase-1; cyclooxygenase-2; anti-inflammatory activity; analgesic activity

Hrčak ID: 22932

URI
https://hrcak.srce.hr/22932

[hrvatski]

Posjeta: 1.272 *