Stručni rad
https://doi.org/10.20471/acc.2020.59.s1.17
The Association Between Type 2 Diabetes Mellitus, Hypothyroidism, and Thyroid Cancer
Željko Zubčić
; Department of Otorhinolaryngology and Maxillofacial Surgery, Osijek Medical Faculty, University J.J. Strossmayer Osijek, Osijek, Croatia; Department of Otorhinolaryngology and Head and Neck Surgery, Osijek Clinical Hospital Centre, Osijek, Croatia
Anamarija Šestak
; Department of Otorhinolaryngology, Vukovar General Hospital, Vukovar, Croatia
Hrvoje Mihalj
; Department of Otorhinolaryngology and Maxillofacial Surgery, Osijek Medical Faculty, University J.J. Strossmayer Osijek, Osijek, Croatia; Department of Otorhinolaryngology and Head and Neck Surgery, Osijek Clinical Hospital Centre, Osijek, Croatia
Željko Kotromanović
; Department of Otorhinolaryngology and Maxillofacial Surgery, Osijek Medical Faculty, University J.J. Strossmayer Osijek, Osijek, Croatia; Department of Otorhinolaryngology and Head and Neck Surgery, Osijek Clinical Hospital Centre, Osijek, Croatia
Andrijana Včeva
; Department of Otorhinolaryngology and Maxillofacial Surgery, Osijek Medical Faculty, University J.J. Strossmayer Osijek, Osijek, Croatia; Department of Otorhinolaryngology and Head and Neck Surgery, Osijek Clinical Hospital Centre, Osijek, Croatia
Tin Prpić
; Department of Otorhinolaryngology and Head and Neck Surgery, Osijek Clinical Hospital Centre, Osijek, Croatia
Matej Rezo
; Department of Otorhinolaryngology and Head and Neck Surgery, Osijek Clinical Hospital Centre, Osijek, Croatia
Stjepan Grga Milanković
; Department of Otorhinolaryngology and Head and Neck Surgery, Osijek Clinical Hospital Centre, Osijek, Croatia
Vjeran Bogović
; Department of Otorhinolaryngology and Head and Neck Surgery, Osijek Clinical Hospital Centre, Osijek, Croatia
Ivan Abičić
; Department of Otorhinolaryngology and Head and Neck Surgery, Osijek Clinical Hospital Centre, Osijek, Croatia
Sažetak
This study aimed to investigate the association between type 2 diabetes mellitus
(T2DM), antidiabetic therapy, hypothyroidism, and thyroid cancer. We analyzed data from 320 patients
who underwent thyroid surgery for suspicion of cancer. The diagnosis of thyroid cancer was
confirmed by histopathological analysis in 95 patients. No significant difference was found in the diagnosis
of T2DM and hypothyroidism concerning the presence of thyroid cancer (p=0.13; p=0.85),
nor in the gender of patients with T2DM and hypothyroidism with respect to the type of thyroid
cancer (p=0.19; p=0.25). Patients with T2DM (Odds ratio [OR] 1.89; 95% CI, 0.856-4.163) and
patients with hypothyroidism (OR, 1.05; 95% CI, 0.530-2.164) had higher prevalence of thyroid
cancer, as did those who had both diagnoses combined (p=0.37; OR, 2.39; 95% CI, 0.333-17.278),
compared with the patients who did not have those diagnoses. Men with T2DM (OR, 6.19; 95% CI,
1.180-32.513) had higher prevalence of thyroid cancer than women. Patients who were on oral antidiabetics
(OR, 1.91; 95% CI, 0.804-4.512) had higher prevalence of thyroid cancer than those receiving
insulin. According to the results of this study, we can conclude that there is an association between
T2DM, hypothyroidism, oral antidiabetics, and thyroid cancer.
Ključne riječi
type 2 diabetes mellitus; hypothyroidism; thyroid cancer
Hrčak ID:
248286
URI
Datum izdavanja:
1.11.2020.
Posjeta: 1.278 *