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A syntesis of β-Phthalimidopropionaldehyde

I. Jambrešić ; Chemical Institute, Faculty of Science, University of Zagreb
D. Sunko ; Chemical Institute, Faculty of Science, University of Zagreb

Sažetak

Phthaloyl derivatives of amino acids have proved very useful for the further synthesis of compounds in this series. Applyinig this method and the Rosenmund-Zetsche reduction E. Radde prepared a-phthalimidopropionaldehyde from a-phthalimidopropionylchloride. In the same manner we have obtained from B-phthalimidoproplionylchloride B-phthalimidopropionaldehyde as a crystalline solid in 90% yield. This aldehyde was prepared first by Moe and Warner from phthalimide and acrolein in 26% yield. As a new compound we have prepared the semicarbazone of this aldehyde, m. p. 225.5-226°.

Ključne riječi

Hrčak ID:

249887

URI

https://hrcak.srce.hr/249887

Datum izdavanja:

31.10.1952.

Posjeta: 343 *