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https://doi.org/10.18054/pb.v121-122i1-2.10268

Determinants of thyroid volume in healthy young adults of Dalmatia

Tatijana Zemunik ; University of Split, School of Medicine Split, Split, Croatia
Ivana Gunjača   ORCID icon orcid.org/0000-0002-7056-6443 ; University of Split, School of Medicine
Vesela Torlak ; University Hospital Split
Roko Škrabić ; School of Medicine, Split
Marina Vujičević ; School of Medicine, Split
Ana Barić ; University Hospital Split
Marko Vuletić ; University Hospital Split
Veselin Škrabić ; University Hospital Split
Ante Punda ; University Hospital Split
Antonela Matana ; Faculty of Science, Split

Puni tekst: engleski, pdf (225 KB) str. 65-69 preuzimanja: 38* citiraj
APA 6th Edition
Zemunik, T., Gunjača, I., Torlak, V., Škrabić, R., Vujičević, M., Barić, A., ... Matana, A. (2020). Determinants of thyroid volume in healthy young adults of Dalmatia. Periodicum biologorum, 121-122 (1-2), 65-69. https://doi.org/10.18054/pb.v121-122i1-2.10268
MLA 8th Edition
Zemunik, Tatijana, et al. "Determinants of thyroid volume in healthy young adults of Dalmatia." Periodicum biologorum, vol. 121-122, br. 1-2, 2020, str. 65-69. https://doi.org/10.18054/pb.v121-122i1-2.10268. Citirano 16.05.2021.
Chicago 17th Edition
Zemunik, Tatijana, Ivana Gunjača, Vesela Torlak, Roko Škrabić, Marina Vujičević, Ana Barić, Marko Vuletić, Veselin Škrabić, Ante Punda i Antonela Matana. "Determinants of thyroid volume in healthy young adults of Dalmatia." Periodicum biologorum 121-122, br. 1-2 (2020): 65-69. https://doi.org/10.18054/pb.v121-122i1-2.10268
Harvard
Zemunik, T., et al. (2020). 'Determinants of thyroid volume in healthy young adults of Dalmatia', Periodicum biologorum, 121-122(1-2), str. 65-69. https://doi.org/10.18054/pb.v121-122i1-2.10268
Vancouver
Zemunik T, Gunjača I, Torlak V, Škrabić R, Vujičević M, Barić A i sur. Determinants of thyroid volume in healthy young adults of Dalmatia. Periodicum biologorum [Internet]. 2020 [pristupljeno 16.05.2021.];121-122(1-2):65-69. https://doi.org/10.18054/pb.v121-122i1-2.10268
IEEE
T. Zemunik, et al., "Determinants of thyroid volume in healthy young adults of Dalmatia", Periodicum biologorum, vol.121-122, br. 1-2, str. 65-69, 2020. [Online]. https://doi.org/10.18054/pb.v121-122i1-2.10268

Sažetak

Background and purpose: The aim of this study was to investigate thyroid volume (TV) and its determinants in healthy young adults without present or previous thyroid disease.


Materials and methods: The study was performed in a sample of 145 healthy young participants aged 19-29 years, living in an iodine-sufficient area of Dalmatia. Dimensions of the thyroid gland were obtained by ultrasound and used to determine TV. Anthropometric data was collected, and measurements of serum TSH, fT4, Tg, TgAb, and TPOAb levels were determined. Correlations between TV and other continuous variables were determined using the Pearson correlation test, while multivariate linear regression analysis was used to determine the associations of the potential predictors for the TV.


Results: TV in men was larger than in women (p=3.53x10-8) and was positively correlated with anthropometric measurements, with the highest correlation coefficient for height (r=0.53, p=6.36x10-12), then body surface area, BSA (r=0.48, p=1.68x10-9), weight (r=0.43, p=8.28x10-8) and body mass index, BMI (r=0.17, p=0.04). Age and cigarette smoking did not appear to be significantly associated with TV (p=0.13 and p=0.95, respectively). Univariate analysis showed TV correlated with fT4 plasma levels (r=0.35, 1.73x10-5), while multivariate analysis showed height and fT4 levels to be important parameters with a significant role in TV.


Conclusions: We confirmed previously observed association of TV with sex and anthropometric parameters and reported a significant correlation between TV and fT4 levels. Furthermore, fT4 levels and height were found to be the important parameters for predicting TV.

Hrčak ID: 254649

URI
https://hrcak.srce.hr/254649

Posjeta: 69 *