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https://doi.org/10.20471/acc.2021.60.01.15

Evaluation of the Relationship of MPV, RDW and PVI Parameters with Disease Severity in Covid-19 Patients

Dilek Atik orcid id orcid.org/0000-0002-3270-8711 ; Department of Emergency Medicine, Yozgat Bozok University, Yozgat, Turkey
Hasan Burak Kaya orcid id orcid.org/0000-0001-8851-2614 ; Department of Emergency Medicine, Yozgat Bozok University, Yozgat, Turkey


Puni tekst: engleski pdf 390 Kb

str. 103-113

preuzimanja: 475

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Sažetak

Coronavirus was first detected in three severe pneumonia cases in Wuhan, China,
in December 2019. Studies on red cell distribution width (RDW-CV) and mean platelet volume
(MPV) laboratory parameters, which can be examined in complete blood count in COVID-19 patients,
are still very limited. However, to the best of our knowledge, there are no studies examining the
relationship between platelet volume index (PVI) and disease severity in COVID-19 patients, which
was evaluated in this study. The aim of this study was to evaluate the relationship of disease severity in
COVID-19 patients with their MPV, RDW, and PVI parameters. The study included 92 COVID-19
patients as a study group and 84 healthy individuals as control group. All laboratory data and radiological
images were scanned retrospectively from patient files and hospital information system. Evaluation
of the RDW-CV and MPV blood parameters, and PVI measured in COVID-19 patients yielded
statistically significant differences according to the disease severity. We suggest that RDW-CV and
PVI, evaluated within the scope of the study, may be the parameters that should be considered in the
early diagnosis of the disease, from the initial stages of COVID-19. In addition, we think that the
RDW-CV and MPV laboratory parameters, as well as PVI, which all are simple, inexpensive and
widely used hematologic tests, can be used as important biomarkers in determining COVID-19 severity
and mortality.

Ključne riječi

COVID-19; Disease severity; Mean platelet volume; Red cell distribution width; Platelet volume index

Hrčak ID:

259900

URI

https://hrcak.srce.hr/259900

Datum izdavanja:

1.3.2021.

Podaci na drugim jezicima: hrvatski

Posjeta: 1.329 *