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https://doi.org/10.20471/acc.2021.60.01.16

Admission Cardiac Troponins Predict Hospital Mortality in Type a Acute Aortic Dissection: a Meta-Analysis of Adjusted Risk Estimates

Mislav Vrsalović ; University of Zagreb, School of Medicine, Zagreb, Croatia; Department of Cardiology, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia
Ana Vrsalović Presečki ; Faculty of Chemical Engineering and Technology, University of Zagreb, Zagreb, Croatia


Puni tekst: engleski pdf 233 Kb

str. 115-118

preuzimanja: 276

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Sažetak

Acute aortic dissection (AAD) is a serious medical emergency that requires early
diagnosis and rapid treatment. Whether cardiac troponin could be an independent prognostic marker
in patients with type A AAD is still unknown. We systematically searched Medline and Scopus to
identify all observational cohort studies published before January 2020 that compared outcome (inhospital
mortality) in patients with type A AAD with and without troponin elevation on admission.
Four studies with 412 patients were included in final analysis (median age 59 years, 65% of males). A
total of 124 (30%) patients died during in-hospital stay, and 73% underwent surgery. Elevated troponins
(39.6% of patients) were associated with an increased risk of short-term mortality (adjusted odds
ratio 1.26; 95% confidence interval 1.08-1.47), with low heterogeneity among studies (I2=29.81%).
Elevated troponins on admission are independently associated with increased in-hospital mortality in
type A AAD.

Ključne riječi

Troponin; Aortic dissection; Mortality; Meta-analysis

Hrčak ID:

259902

URI

https://hrcak.srce.hr/259902

Datum izdavanja:

1.3.2021.

Podaci na drugim jezicima: hrvatski

Posjeta: 1.172 *