Medicus, Vol. 30 No. 2 Astma i KOPB, 2021.
Pregledni rad
Registries of Patients with Chronic Obstructive Pulmonary Diseases – Why Are They Important?
Vojislav Ćupurdija
Branislava Milenković
Vladimir Žugić
Ivana Stanković
Biljana Zvezdin
Sanja Hromiš
Zorica Lazić
Sažetak
COPD is most probably not just a single disease, but a syndrome made up of numerous individual overlapping diseases. The concept of phenotyping COPD patients would not be feasible without major population-based studies and patient registries. The aim of setting up a COPD registry has been defined as the need to establish the disease prevalence, phenotype incidence, clinical features, co-morbidities, treatment specificities, together with monitoring of the disease’s natural course and its outcome on a large sample of patients. In Serbia, an online registry of COPD patients has been operational since 2016, and the recent insight (before the manuscript’s submission) shows over 4,200 entries.
Analysis of the population of patients entered shows that an average patient is male (63%), smoker or ex-smoker (90.48%), over 60 years of age (82.01%). Pulmonary function analysis shows that the majority of enrolled patients (82%) have moderate to severe obstruction, with an average FEV1 of 52.82% of the predicted value, while 45% of patients have FEV1 value below 50% of the predicted value. The Charlson Comorbidity Index shows that half of the patients (49.97%) have one comorbidity. Most common comorbidities are arterial hypertension, diabetes mellitus, liver disease, congestive heart failure, and coronary ischemic disease. Comorbidities such as osteoporosis, depression, and anxiety have been reported very rarely. The phenotype analysis showed equal shares of two predominant groups: non-exacerbators (51.12%), and exacerbators (48.88%) within which there are groups of patients with pulmonary emphysema (34.35%) and patients with chronic bronchitis (14.53%). The data indicate that strategy for COPD treatment in our environment is changing towards adoption of modern recommendations and guidelines for treatment of this disease.
The data enable a comprehensive insight into the disease and drawing up of feasible treatment strategies that give us hope for success.
Ključne riječi
Chronic Obstructive Pulmonary Disease; COPD; registry; phenotype
Hrčak ID:
264152
URI
Datum izdavanja:
18.10.2021.
Posjeta: 749 *