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Identification and Analysis of cDNAs Encoding Two Nucleoside Diphosphate Kinases (NDPK/Nm23) from the Marine Sponge Suberites domuncula

Matija Harcet
Lada Lukić-Bilela
Helena Ćetković
Werner E. G. Müller
Vera Gamulin

Puni tekst: engleski, pdf (270 KB) str. 343-348 preuzimanja: 414* citiraj
APA 6th Edition
Harcet, M., Lukić-Bilela, L., Ćetković, H., Müller, W.E.G. i Gamulin, V. (2005). Identification and Analysis of cDNAs Encoding Two Nucleoside Diphosphate Kinases (NDPK/Nm23) from the Marine Sponge Suberites domuncula. Croatica Chemica Acta, 78 (3), 343-348. Preuzeto s https://hrcak.srce.hr/40
MLA 8th Edition
Harcet, Matija, et al. "Identification and Analysis of cDNAs Encoding Two Nucleoside Diphosphate Kinases (NDPK/Nm23) from the Marine Sponge Suberites domuncula." Croatica Chemica Acta, vol. 78, br. 3, 2005, str. 343-348. https://hrcak.srce.hr/40. Citirano 22.11.2019.
Chicago 17th Edition
Harcet, Matija, Lada Lukić-Bilela, Helena Ćetković, Werner E. G. Müller i Vera Gamulin. "Identification and Analysis of cDNAs Encoding Two Nucleoside Diphosphate Kinases (NDPK/Nm23) from the Marine Sponge Suberites domuncula." Croatica Chemica Acta 78, br. 3 (2005): 343-348. https://hrcak.srce.hr/40
Harvard
Harcet, M., et al. (2005). 'Identification and Analysis of cDNAs Encoding Two Nucleoside Diphosphate Kinases (NDPK/Nm23) from the Marine Sponge Suberites domuncula', Croatica Chemica Acta, 78(3), str. 343-348. Preuzeto s: https://hrcak.srce.hr/40 (Datum pristupa: 22.11.2019.)
Vancouver
Harcet M, Lukić-Bilela L, Ćetković H, Müller WEG, Gamulin V. Identification and Analysis of cDNAs Encoding Two Nucleoside Diphosphate Kinases (NDPK/Nm23) from the Marine Sponge Suberites domuncula. Croatica Chemica Acta [Internet]. 2005 [pristupljeno 22.11.2019.];78(3):343-348. Dostupno na: https://hrcak.srce.hr/40
IEEE
M. Harcet, L. Lukić-Bilela, H. Ćetković, W.E.G. Müller i V. Gamulin, "Identification and Analysis of cDNAs Encoding Two Nucleoside Diphosphate Kinases (NDPK/Nm23) from the Marine Sponge Suberites domuncula", Croatica Chemica Acta, vol.78, br. 3, str. 343-348, 2005. [Online]. Dostupno na: https://hrcak.srce.hr/40. [Citirano: 22.11.2019.]

Sažetak
Suberites domuncula is a member of the most ancient and simplest extant phylum of multicellular animals – sponges (Porifera). A database of S. domuncula expressed sequence tags (ESTs) was recently constructed by random cDNA sequencing. Two NDPK/Nm23 proteins from the sponge Suberites domuncula are reported here. Sponge proteins were named Nm23-SD1 and Nm23-SD6, because they display the highest sequence similarity with human Nm23-H1 and -H6 proteins. Overall sequence conservation of Nm23-SD1 with human Nm23-H1 is very high – 79 % (71 % identical amino acids). Nm23-SD6 possesses an insertion at the C-terminus and displays 55 % overall homology (40 % identical amino acids) with human Nm23 H6. Secondary structure predictions for both sponge and human Nm23 protein pairs are almost identical. S. domuncula Nm23 proteins display high similarity to homologues from mammals/humans, higher than to e.g. NDPK/Nm23 proteins from Drosophila or other invertebrates. Sponge Nm23 proteins are more similar to mammalian/human Nm23 proteins than most known Nm23 proteins of invertebrates.

Ključne riječi
antimetastatic proteins; nucleoside diphosphate kinases; sponge cDNA library; Porifera

Hrčak ID: 40

URI
https://hrcak.srce.hr/40

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