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Effect of Olanzapine on Disruptive Behavior in Institutionalized Patients with Severe Intellectual Disability – A Case Series

Stipe Drmić
Tomislav Franić

Puni tekst: engleski, pdf (153 KB) str. 325-330 preuzimanja: 291* citiraj
APA 6th Edition
Drmić, S. i Franić, T. (2008). Effect of Olanzapine on Disruptive Behavior in Institutionalized Patients with Severe Intellectual Disability – A Case Series. Collegium antropologicum, 32 (2), 325-330. Preuzeto s https://hrcak.srce.hr/27208
MLA 8th Edition
Drmić, Stipe i Tomislav Franić. "Effect of Olanzapine on Disruptive Behavior in Institutionalized Patients with Severe Intellectual Disability – A Case Series." Collegium antropologicum, vol. 32, br. 2, 2008, str. 325-330. https://hrcak.srce.hr/27208. Citirano 20.11.2019.
Chicago 17th Edition
Drmić, Stipe i Tomislav Franić. "Effect of Olanzapine on Disruptive Behavior in Institutionalized Patients with Severe Intellectual Disability – A Case Series." Collegium antropologicum 32, br. 2 (2008): 325-330. https://hrcak.srce.hr/27208
Harvard
Drmić, S., i Franić, T. (2008). 'Effect of Olanzapine on Disruptive Behavior in Institutionalized Patients with Severe Intellectual Disability – A Case Series', Collegium antropologicum, 32(2), str. 325-330. Preuzeto s: https://hrcak.srce.hr/27208 (Datum pristupa: 20.11.2019.)
Vancouver
Drmić S, Franić T. Effect of Olanzapine on Disruptive Behavior in Institutionalized Patients with Severe Intellectual Disability – A Case Series. Collegium antropologicum [Internet]. 2008 [pristupljeno 20.11.2019.];32(2):325-330. Dostupno na: https://hrcak.srce.hr/27208
IEEE
S. Drmić i T. Franić, "Effect of Olanzapine on Disruptive Behavior in Institutionalized Patients with Severe Intellectual Disability – A Case Series", Collegium antropologicum, vol.32, br. 2, str. 325-330, 2008. [Online]. Dostupno na: https://hrcak.srce.hr/27208. [Citirano: 20.11.2019.]

Sažetak
Considerable number of intellectual disabled people experience some form of disruptive behavior. Antipsychotics are
the most common treatment for these behaviors. Numerous patients were efficiently treated with thioridazine, recently
withdrawn. The authors describe a case series of »thioridazine responders« treated with olanzapine. Thirty three patients
with severe intellectual disability were recruited. All patients were assessed for seven types of disruptive behavior on five
point scale. Patients with severe behavior disturbances were included in treatment. The time points of assessment were
at day 0, 30, 60 and 180. Twenty one patient accomplished inclusion criteria. A significant decrease occurred at day 30
for all types of behavior. Total score, self injurious behavior, compulsive and destructive behavior showed further decrease
at day 60 and became stable until the end of study. Olanzapine appears to be efficacious in the treatment of disruptive
behavior in the intellectually disabled and could be substitute for thioridazine treatment.

Ključne riječi
intellectual disability; disruptive behavior; antipsychotics; olanzapine

Hrčak ID: 27208

URI
https://hrcak.srce.hr/27208

Posjeta: 428 *