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Subacute Sclerosing Panencephalitis – The Continuing Threat

Tatjana Vilibić Čavlek
Sunčanica Ljubin Sternak
Kamelija Žarković
Branka Marušić Della Marina
Ljerka Cvitanović Šojat
Anica Bašnec
Bernard Kaić
Branko Turković
Gordana Mlinarić Galinović

Puni tekst: engleski, pdf (167 KB) str. 959-963 preuzimanja: 566* citiraj
APA 6th Edition
Vilibić Čavlek, T., Ljubin Sternak, S., Žarković, K., Marušić Della Marina, B., Cvitanović Šojat, Lj., Bašnec, A., ... Mlinarić Galinović, G. (2006). Subacute Sclerosing Panencephalitis – The Continuing Threat. Collegium antropologicum, 30 (4), 959-963. Preuzeto s
MLA 8th Edition
Vilibić Čavlek, Tatjana, et al. "Subacute Sclerosing Panencephalitis – The Continuing Threat." Collegium antropologicum, vol. 30, br. 4, 2006, str. 959-963. Citirano 21.10.2020.
Chicago 17th Edition
Vilibić Čavlek, Tatjana, Sunčanica Ljubin Sternak, Kamelija Žarković, Branka Marušić Della Marina, Ljerka Cvitanović Šojat, Anica Bašnec, Bernard Kaić, Branko Turković i Gordana Mlinarić Galinović. "Subacute Sclerosing Panencephalitis – The Continuing Threat." Collegium antropologicum 30, br. 4 (2006): 959-963.
Vilibić Čavlek, T., et al. (2006). 'Subacute Sclerosing Panencephalitis – The Continuing Threat', Collegium antropologicum, 30(4), str. 959-963. Preuzeto s: (Datum pristupa: 21.10.2020.)
Vilibić Čavlek T, Ljubin Sternak S, Žarković K, Marušić Della Marina B, Cvitanović Šojat Lj, Bašnec A i sur. Subacute Sclerosing Panencephalitis – The Continuing Threat. Collegium antropologicum [Internet]. 2006 [pristupljeno 21.10.2020.];30(4):959-963. Dostupno na:
T. Vilibić Čavlek, et al., "Subacute Sclerosing Panencephalitis – The Continuing Threat", Collegium antropologicum, vol.30, br. 4, str. 959-963, 2006. [Online]. Dostupno na: [Citirano: 21.10.2020.]

Clinical, epidemiological and laboratory findings of four patients with subacute sclerosing panencephalitis (SSPE),
diagnosed in Croatia in 2002, were examined. Patient age at disease onset ranged from 5–11 years. All patients were vaccinated
regularly with MMR-vaccine. Two patients had a history of measles infection at the age of six and seven months,
respectively. In the other two patients, the disease started immediately after the varicella infection. Complement fixing
antibody titre to the measles virus (MV) ranged from 1:1024 to 1:65536 in serum, and from 1:16 to 1:128 in cerebrospinal
fluid (CSF). In CSF, no antibodies to varicella-zoster virus were found. Brain tissue samples were obtained at autopsy
from two patients. In one patient, electron microscopy demonstrated intranuclear viral inclusions (MV nucleocapsids).
MV antigen was detected in brain imprints using IFA in both of them. Viral RNA was found in brain tissue samples only,
while plasma, serum and CSF were negative. Nucleotide sequence analysis showed that the viruses detected in brain tissue
belong to the wild-type MV D6 genotype14.

Ključne riječi
subacute sclerosing panencephalitis; measles; MMR

Hrčak ID: 27689


Posjeta: 766 *