 |
|
 |
Izvorni znanstveni članak
Synthetic Modifications of Ascomycin. V. Access to Novel Ascomycin Derivatives by Replacement of the Cyclohexylvinylidene Subunit
Reinhold Zimmer
Karl Baumann
Hildegard Sperner
Gerhard Schulz
Ewald Haidl
Maximilian A. Grassberger
| Puni tekst: engleski, pdf (161 KB) | str. 17-27 | citiraj | |
|
APA 6th Edition Zimmer, R., Baumann, K., Sperner, H., Schulz, G., Haidl, E. i Grassberger, M.A. (2005). Synthetic Modifications of Ascomycin. V. Access to Novel Ascomycin Derivatives by Replacement of the Cyclohexylvinylidene Subunit. Croatica Chemica Acta, 78 (1), 17-27. Preuzeto s https://hrcak.srce.hr/2661 MLA 8th Edition Zimmer, Reinhold, et al. "Synthetic Modifications of Ascomycin. V. Access to Novel Ascomycin Derivatives by Replacement of the Cyclohexylvinylidene Subunit." Croatica Chemica Acta, vol. 78, br. 1, 2005, str. 17-27. https://hrcak.srce.hr/2661. Citirano 26.02.2021. Chicago 17th Edition Zimmer, Reinhold, Karl Baumann, Hildegard Sperner, Gerhard Schulz, Ewald Haidl i Maximilian A. Grassberger. "Synthetic Modifications of Ascomycin. V. Access to Novel Ascomycin Derivatives by Replacement of the Cyclohexylvinylidene Subunit." Croatica Chemica Acta 78, br. 1 (2005): 17-27. https://hrcak.srce.hr/2661 Harvard Zimmer, R., et al. (2005). 'Synthetic Modifications of Ascomycin. V. Access to Novel Ascomycin Derivatives by Replacement of the Cyclohexylvinylidene Subunit', Croatica Chemica Acta, 78(1), str. 17-27. Preuzeto s: https://hrcak.srce.hr/2661 (Datum pristupa: 26.02.2021.) Vancouver Zimmer R, Baumann K, Sperner H, Schulz G, Haidl E, Grassberger MA. Synthetic Modifications of Ascomycin. V. Access to Novel Ascomycin Derivatives by Replacement of the Cyclohexylvinylidene Subunit. Croatica Chemica Acta [Internet]. 2005 [pristupljeno 26.02.2021.];78(1):17-27. Dostupno na: https://hrcak.srce.hr/2661 IEEE R. Zimmer, K. Baumann, H. Sperner, G. Schulz, E. Haidl i M.A. Grassberger, "Synthetic Modifications of Ascomycin. V. Access to Novel Ascomycin Derivatives by Replacement of the Cyclohexylvinylidene Subunit", Croatica Chemica Acta, vol.78, br. 1, str. 17-27, 2005. [Online]. Dostupno na: https://hrcak.srce.hr/2661. [Citirano: 26.02.2021.] |
|||
Sažetak
Starting from the easily accessible 24-O-tert-butyldimethylsilyl-22(R)-dihydro-28-oxoascomycin, methodologies that allow replacement of the cyclohexylvinylidene moiety of ascomycin by various other substituents are described. In addition, a so far unknown reactivity of the masked tricarbonyl moiety of ascomycin towards a stabilized Wittig reagent is reported.
Ključne riječi
ascomycin; immunosuppressiva; aldol reaction; oxime; Wittig reaction; oxidation
Hrčak ID: 2661
Moj profil
Srce