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Expression of Vascular Endothelial Growth Factor in Proliferative Diabetic Retinopathy

Maja Merlak
Damir Kovačević
Tihomir Balog
Tanja Marotti
Tamara Mišljenović
Maša Mikuličić
Iva Dekaris

Puni tekst: engleski, pdf (101 KB) str. 39-43 preuzimanja: 452* citiraj
APA 6th Edition
Merlak, M., Kovačević, D., Balog, T., Marotti, T., Mišljenović, T., Mikuličić, M. i Dekaris, I. (2008). Expression of Vascular Endothelial Growth Factor in Proliferative Diabetic Retinopathy. Collegium antropologicum, 32 - Supplement 2 (2), 39-43. Preuzeto s https://hrcak.srce.hr/34537
MLA 8th Edition
Merlak, Maja, et al. "Expression of Vascular Endothelial Growth Factor in Proliferative Diabetic Retinopathy." Collegium antropologicum, vol. 32 - Supplement 2, br. 2, 2008, str. 39-43. https://hrcak.srce.hr/34537. Citirano 17.06.2021.
Chicago 17th Edition
Merlak, Maja, Damir Kovačević, Tihomir Balog, Tanja Marotti, Tamara Mišljenović, Maša Mikuličić i Iva Dekaris. "Expression of Vascular Endothelial Growth Factor in Proliferative Diabetic Retinopathy." Collegium antropologicum 32 - Supplement 2, br. 2 (2008): 39-43. https://hrcak.srce.hr/34537
Harvard
Merlak, M., et al. (2008). 'Expression of Vascular Endothelial Growth Factor in Proliferative Diabetic Retinopathy', Collegium antropologicum, 32 - Supplement 2(2), str. 39-43. Preuzeto s: https://hrcak.srce.hr/34537 (Datum pristupa: 17.06.2021.)
Vancouver
Merlak M, Kovačević D, Balog T, Marotti T, Mišljenović T, Mikuličić M i sur. Expression of Vascular Endothelial Growth Factor in Proliferative Diabetic Retinopathy. Collegium antropologicum [Internet]. 2008 [pristupljeno 17.06.2021.];32 - Supplement 2(2):39-43. Dostupno na: https://hrcak.srce.hr/34537
IEEE
M. Merlak, et al., "Expression of Vascular Endothelial Growth Factor in Proliferative Diabetic Retinopathy", Collegium antropologicum, vol.32 - Supplement 2, br. 2, str. 39-43, 2008. [Online]. Dostupno na: https://hrcak.srce.hr/34537. [Citirano: 17.06.2021.]

Sažetak
The study included 20 patients with diabetes mellitus type I (DM I) and 16 with type II (DM II) suffering from
prolipherative diabetic retinopathy (PDR) for which they underwent vitrectomy. The quantity of VEGF and its receptors
in the vitreous of investigated patients were measured by immunoassay and results compared between patients with DM
I and II. The mean levels in the vitreous were significantly higher in diabetics with PDR and diabetes mellitus I (432.2
pg/mL, 1460.4 pg/mL and 1054.6 pg/mL) than in diabetics with PDR and diabetes mellitus II (147.5 pg/mL, 641.4
pg/mL and 448.5 pg/mL) and in control group (63.26 pg/mL). Considering that VEGF, VEGFR1 and VEGFR2 levels
were significantly higher in diabetics with PDR than in controls and that the patients with DM I had higher levels than
with DM II, anti-VEGF therapy might be beneficial for diabetics with PDR, especially those with DM I.

Ključne riječi
vascular endothelial growth factor – VEGF; VEGF receptor; vitreous; proliferative diabetic retinopathy

Hrčak ID: 34537

URI
https://hrcak.srce.hr/34537

Posjeta: 633 *