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Nevus Spitz – Everlasting Diagnostic Difficulties – The Review

Mirna Šitum
Željana Bolanča
Marija Buljan
Davor Tomas
Marijana Ivančić

Puni tekst: engleski, pdf (173 KB) str. 171-176 preuzimanja: 1.593* citiraj
APA 6th Edition
Šitum, M., Bolanča, Ž., Buljan, M., Tomas, D. i Ivančić, M. (2008). Nevus Spitz – Everlasting Diagnostic Difficulties – The Review. Collegium antropologicum, 32 - Supplement 2 (2), 171-176. Preuzeto s
MLA 8th Edition
Šitum, Mirna, et al. "Nevus Spitz – Everlasting Diagnostic Difficulties – The Review." Collegium antropologicum, vol. 32 - Supplement 2, br. 2, 2008, str. 171-176. Citirano 17.06.2021.
Chicago 17th Edition
Šitum, Mirna, Željana Bolanča, Marija Buljan, Davor Tomas i Marijana Ivančić. "Nevus Spitz – Everlasting Diagnostic Difficulties – The Review." Collegium antropologicum 32 - Supplement 2, br. 2 (2008): 171-176.
Šitum, M., et al. (2008). 'Nevus Spitz – Everlasting Diagnostic Difficulties – The Review', Collegium antropologicum, 32 - Supplement 2(2), str. 171-176. Preuzeto s: (Datum pristupa: 17.06.2021.)
Šitum M, Bolanča Ž, Buljan M, Tomas D, Ivančić M. Nevus Spitz – Everlasting Diagnostic Difficulties – The Review. Collegium antropologicum [Internet]. 2008 [pristupljeno 17.06.2021.];32 - Supplement 2(2):171-176. Dostupno na:
M. Šitum, Ž. Bolanča, M. Buljan, D. Tomas i M. Ivančić, "Nevus Spitz – Everlasting Diagnostic Difficulties – The Review", Collegium antropologicum, vol.32 - Supplement 2, br. 2, str. 171-176, 2008. [Online]. Dostupno na: [Citirano: 17.06.2021.]

In 1910, Darier and Civatte described in details an unusual melanocytic tumor characterized by rapid growth on the
nose of a young child. They could not state whether the tumor was benign or malignant. In 1947, Sophie Spitz described
the same lesion as juvenile melanoma in which prognosis was frequently excellent. Later, the study was revised and it
was concluded that juvenile melanoma was a benign tumor and can affect adults. Although, the prognosis was mostly
excellent, Spitz reported in one of 13 cases fatal metastases from nevus Spitz. In 1999, Barnhill et al described one fatal
case of the patient for whom it was thought to have typical Spitz nevus. Nowadays, there is still a lack of consensus about
histopathology and also a terminology of the tumors that are neither typical nevus Spitz, neither malignant melanoma.
All histopathological, clinical and ancillary criteria must be weighed in the final interpretation of epitheloid/spindle cell
lesion. At the present, the final diagnosis remains pathohistological, with important emphasis given to clinical impression.
Persistently changing lesion indicates malignancy potential of the lesion. Barnhill recommends that all Spitz tumors
are completely excised. Atypical tumors should be excised with wider margins up to 1 cm. Patient should be carefully
monitored by regular examinations for recurrence and metastasis.

Ključne riječi
nevus Spitz; atypical nevus Spitz; Spitzoid melanoma; pathohistological analysis; surgical excision

Hrčak ID: 34647


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