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Arhiv za higijenu rada i toksikologiju, Vol. 49 No. 2, 1998.
Pregledni rad
Multiple Chemical Sensitivity: Theories of Etiopathogenesis
Željko Ugrenović
Jasminka Bobić
| Puni tekst: hrvatski, pdf (356 KB) | str. 189-205 | citiraj | |
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APA 6th Edition Ugrenović, Ž. i Bobić, J. (1998). Višestruka kemijska osjetljivost: teorije etiopatogeneze. Arhiv za higijenu rada i toksikologiju, 49 (2), 189-205. Preuzeto s https://hrcak.srce.hr/3314 MLA 8th Edition Ugrenović, Željko i Jasminka Bobić. "Višestruka kemijska osjetljivost: teorije etiopatogeneze." Arhiv za higijenu rada i toksikologiju, vol. 49, br. 2, 1998, str. 189-205. https://hrcak.srce.hr/3314. Citirano 27.05.2019. Chicago 17th Edition Ugrenović, Željko i Jasminka Bobić. "Višestruka kemijska osjetljivost: teorije etiopatogeneze." Arhiv za higijenu rada i toksikologiju 49, br. 2 (1998): 189-205. https://hrcak.srce.hr/3314 Harvard Ugrenović, Ž., i Bobić, J. (1998). 'Višestruka kemijska osjetljivost: teorije etiopatogeneze', Arhiv za higijenu rada i toksikologiju, 49(2), str. 189-205. Preuzeto s: https://hrcak.srce.hr/3314 (Datum pristupa: 27.05.2019.) Vancouver Ugrenović Ž, Bobić J. Višestruka kemijska osjetljivost: teorije etiopatogeneze. Arh Hig Rada Toksikol. [Internet]. 1998 [pristupljeno 27.05.2019.];49(2):189-205. Dostupno na: https://hrcak.srce.hr/3314 IEEE Ž. Ugrenović i J. Bobić, "Višestruka kemijska osjetljivost: teorije etiopatogeneze", Arhiv za higijenu rada i toksikologiju, vol.49, br. 2, str. 189-205, 1998. [Online]. Dostupno na: https://hrcak.srce.hr/3314. [Citirano: 27.05.2019.] |
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Sažetak
Multiple chemical sensitivity (MCS) is a controversial disorder of uncertain etiology, characterized by recurrent symptoms referable to multiple organ systems, occurring as a response to chemically unrelated compounds at doses far below those established to cause harmful effects in the general population. The fundamental question is whether the MCS is primarily a toxicodynamic phenomenon (a pathological interaction between a chemical agent and organ systems, possibly acting through a mechanism different from those known in toxicology) or a psychogenic disorder (an emotional reaction to perceived toxic agents). This paper presents some recent theories of etiopathogenesis of the MCS discussing the role of immunological, inflammatory, metabolic, psychophysiologic, and neurochemical mechanisms, as well as the role of neural sensitization in the etiology of the disorder. The paper foregrounds the complex relation between psychiatric disorders and social factors, on one hand, and the MCS on the other. A particular emphasis is put on the relevance of the MCS research for clinical practice, public health, and regulatory decisions.
Ključne riječi
acquired intolerance; chemical safety; etiopathogenesis; exposure; multiple chemical sensitivity; psychiatric disorders; sensitization
Hrčak ID: 3314
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