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Arhiv za higijenu rada i toksikologiju, Vol. 49 No. 2, 1998.

Pregledni rad

Multiple Chemical Sensitivity: Theories of Etiopathogenesis

Željko Ugrenović
Jasminka Bobić

Puni tekst: hrvatski, pdf (356 KB) str. 189-205 preuzimanja: 850* citiraj
APA 6th Edition
Ugrenović, Ž. i Bobić, J. (1998). Višestruka kemijska osjetljivost: teorije etiopatogeneze. Arhiv za higijenu rada i toksikologiju, 49 (2), 189-205. Preuzeto s https://hrcak.srce.hr/3314
MLA 8th Edition
Ugrenović, Željko i Jasminka Bobić. "Višestruka kemijska osjetljivost: teorije etiopatogeneze." Arhiv za higijenu rada i toksikologiju, vol. 49, br. 2, 1998, str. 189-205. https://hrcak.srce.hr/3314. Citirano 27.05.2019.
Chicago 17th Edition
Ugrenović, Željko i Jasminka Bobić. "Višestruka kemijska osjetljivost: teorije etiopatogeneze." Arhiv za higijenu rada i toksikologiju 49, br. 2 (1998): 189-205. https://hrcak.srce.hr/3314
Harvard
Ugrenović, Ž., i Bobić, J. (1998). 'Višestruka kemijska osjetljivost: teorije etiopatogeneze', Arhiv za higijenu rada i toksikologiju, 49(2), str. 189-205. Preuzeto s: https://hrcak.srce.hr/3314 (Datum pristupa: 27.05.2019.)
Vancouver
Ugrenović Ž, Bobić J. Višestruka kemijska osjetljivost: teorije etiopatogeneze. Arh Hig Rada Toksikol. [Internet]. 1998 [pristupljeno 27.05.2019.];49(2):189-205. Dostupno na: https://hrcak.srce.hr/3314
IEEE
Ž. Ugrenović i J. Bobić, "Višestruka kemijska osjetljivost: teorije etiopatogeneze", Arhiv za higijenu rada i toksikologiju, vol.49, br. 2, str. 189-205, 1998. [Online]. Dostupno na: https://hrcak.srce.hr/3314. [Citirano: 27.05.2019.]

Sažetak
Multiple chemical sensitivity (MCS) is a controversial disorder of uncertain etiology, characterized by recurrent symptoms referable to multiple organ systems, occurring as a response to chemically unrelated compounds at doses far below those established to cause harmful effects in the general population. The fundamental question is whether the MCS is primarily a toxicodynamic phenomenon (a pathological interaction between a chemical agent and organ systems, possibly acting through a mechanism different from those known in toxicology) or a psychogenic disorder (an emotional reaction to perceived toxic agents). This paper presents some recent theories of etiopathogenesis of the MCS discussing the role of immunological, inflammatory, metabolic, psychophysiologic, and neurochemical mechanisms, as well as the role of neural sensitization in the etiology of the disorder. The paper foregrounds the complex relation between psychiatric disorders and social factors, on one hand, and the MCS on the other. A particular emphasis is put on the relevance of the MCS research for clinical practice, public health, and regulatory decisions.

Ključne riječi
acquired intolerance; chemical safety; etiopathogenesis; exposure; multiple chemical sensitivity; psychiatric disorders; sensitization

Hrčak ID: 3314

URI
https://hrcak.srce.hr/3314

[hrvatski]

Posjeta: 1.183 *