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Molecular Imaging Mass Spectrometry

D. Josić ; Sveučilište J. J. Strossmayera u Osijeku, Osijek, Hrvatska; Proteomics Core, Center for Cancer Research Development, Rhode Island, USA
S. Kovač ; Prehrambeno-tehnološki fakultet Osijek, Osijek, Hrvatska, Sveučilište J. J. Strossmayera u Osijeku, Osijek, Hrvatska

Puni tekst: engleski, pdf (1 MB) str. 207-213 preuzimanja: 317* citiraj
APA 6th Edition
Josić, D. i Kovač, S. (2009). Molecular Imaging Mass Spectrometry. Kemija u industriji, 58 (5), 207-213. Preuzeto s https://hrcak.srce.hr/36520
MLA 8th Edition
Josić, D. i S. Kovač. "Molecular Imaging Mass Spectrometry." Kemija u industriji, vol. 58, br. 5, 2009, str. 207-213. https://hrcak.srce.hr/36520. Citirano 15.11.2019.
Chicago 17th Edition
Josić, D. i S. Kovač. "Molecular Imaging Mass Spectrometry." Kemija u industriji 58, br. 5 (2009): 207-213. https://hrcak.srce.hr/36520
Harvard
Josić, D., i Kovač, S. (2009). 'Molecular Imaging Mass Spectrometry', Kemija u industriji, 58(5), str. 207-213. Preuzeto s: https://hrcak.srce.hr/36520 (Datum pristupa: 15.11.2019.)
Vancouver
Josić D, Kovač S. Molecular Imaging Mass Spectrometry. Kemija u industriji [Internet]. 2009 [pristupljeno 15.11.2019.];58(5):207-213. Dostupno na: https://hrcak.srce.hr/36520
IEEE
D. Josić i S. Kovač, "Molecular Imaging Mass Spectrometry", Kemija u industriji, vol.58, br. 5, str. 207-213, 2009. [Online]. Dostupno na: https://hrcak.srce.hr/36520. [Citirano: 15.11.2019.]

Sažetak
Molecular imaging mass spectrometry (IMS) is a recently developed method for direct determination of spatial distribution of biopolymers, preferably proteins on cell surface and tissues. Imaging mass spectrometry data are mainly based on Matrix-Assisted Laser Desorption/Ionization- Time of Flight (MALDI TOF). The MALDI TOF based imaging mass spectrometry was applied for determination of changes in kidney tissue of sensitive mice after poisoning with aristolochic acid I. The second application presented here were changes in the gastric tissue in mice after infection with Helicobacter pylori, as a model of gastric cancer in humans caused by this pathogen microorganism. Molecular imaging mass spectrometry can be applied in medicine, mostly for identification of candidate biomarkers for malignant and non-malignant diseases. Furthermore, imaging MS has almost unlimited capacity in agriculture, food technology and biotechnology, e. g. for monitoring, process development and quality control of manufactured tissue of animal, plant and microbial origin.

Ključne riječi
Imaging mass spectrometry; aristolochic acid; nephropathy; gastric cancer; biomarkers

Hrčak ID: 36520

URI
https://hrcak.srce.hr/36520

[hrvatski]

Posjeta: 878 *