hrcak mascot   Srce   HID

Izvorni znanstveni članak

Effect of Aminglycoside Administration on the Occurrence and Multiplication of Resistant Bacteria

Josip Milas ; Public Health Institute of the Osijek-Baranya County, Osijek, Croatia
Smilja Kalenić ; Zagreb University Hospital Center, Zagreb, Croatia
Vesna Milas ; Osijek University Hospital, Osijek, Croatia
Maja Miškulin ; Public Health Institute of the Osijek-Baranya County, Osijek, Croatia
Dubravka Vuković ; Public Health Institute of the Osijek-Baranya County, Osijek, Croatia
Stjepan Rudan ; Public Health Institute of the Osijek-Baranya County, Osijek, Croatia
Dinko Puntarić ; Public Health Institute »Andrija Štampar«, Zagreb, Croatia

Puni tekst: engleski, pdf (199 KB) str. 579-585 preuzimanja: 206* citiraj
APA 6th Edition
Milas, J., Kalenić, S., Milas, V., Miškulin, M., Vuković, D., Rudan, S. i Puntarić, D. (2009). Effect of Aminglycoside Administration on the Occurrence and Multiplication of Resistant Bacteria. Collegium antropologicum, 33 (2), 579-585. Preuzeto s https://hrcak.srce.hr/40560
MLA 8th Edition
Milas, Josip, et al. "Effect of Aminglycoside Administration on the Occurrence and Multiplication of Resistant Bacteria." Collegium antropologicum, vol. 33, br. 2, 2009, str. 579-585. https://hrcak.srce.hr/40560. Citirano 05.04.2020.
Chicago 17th Edition
Milas, Josip, Smilja Kalenić, Vesna Milas, Maja Miškulin, Dubravka Vuković, Stjepan Rudan i Dinko Puntarić. "Effect of Aminglycoside Administration on the Occurrence and Multiplication of Resistant Bacteria." Collegium antropologicum 33, br. 2 (2009): 579-585. https://hrcak.srce.hr/40560
Harvard
Milas, J., et al. (2009). 'Effect of Aminglycoside Administration on the Occurrence and Multiplication of Resistant Bacteria', Collegium antropologicum, 33(2), str. 579-585. Preuzeto s: https://hrcak.srce.hr/40560 (Datum pristupa: 05.04.2020.)
Vancouver
Milas J, Kalenić S, Milas V, Miškulin M, Vuković D, Rudan S i sur. Effect of Aminglycoside Administration on the Occurrence and Multiplication of Resistant Bacteria. Collegium antropologicum [Internet]. 2009 [pristupljeno 05.04.2020.];33(2):579-585. Dostupno na: https://hrcak.srce.hr/40560
IEEE
J. Milas, et al., "Effect of Aminglycoside Administration on the Occurrence and Multiplication of Resistant Bacteria", Collegium antropologicum, vol.33, br. 2, str. 579-585, 2009. [Online]. Dostupno na: https://hrcak.srce.hr/40560. [Citirano: 05.04.2020.]

Sažetak
In the prospective study the susceptibility of 41 Escherichia coli strains and 55 Pseudomonas aeruginosa strains to gentamicin, netilmicin and amikacin was tested at a 2-year interval (period I April 1998 to March 1999, and period II April to July 2001). Genotyping was performed by pulsed-field gel electrophoresis, and a clone based on 80% or 90% similarity was determined for each of the study bacteria. In 24 (32.0%) clones, strains showed no variation over 2-year interval, supporting the hypothesis on a priori susceptible strains. Transformation from susceptibility in period I to resistance in period II was demonstrated in 5 (6.7%) clones, a pattern consistent with the concept of bacterial development of resistance under the influence of antibiotics. However, there were 10 (13.3%) clones whose strains exhibited an inverse pattern. Accordingly, two-way transformation of susceptibility took place during the study period. The utilization of the study aminoglycosides had no major impact on the variation of microbial susceptibility. Changes in microbial susceptibility were found to follow some regular patterns, which were not influenced by the study aminoglycosides. Two phenomena were observed: (i) there were stable clones that did not develop resistance in spite of selective antibiotic challenge; and (ii) changes of susceptibility in isolated bacteria from both inpatient and outpatient strains of the same clone were two-way and reversible.

Ključne riječi
aminoglycosides; antimicrobial resistance; change of susceptibility; clone; pulsed-field gel electrophoresis; Escherichia coli; Pseudomonas aeruginosa

Hrčak ID: 40560

URI
https://hrcak.srce.hr/40560

Posjeta: 419 *