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Izvorni znanstveni članak
https://doi.org/10.2478/v10007-010-0001-3

Formulation and evaluation of multiple tablets as a biphasic gastroretentivefloating drug delivery system for fenoverine

SURESH BANDARI ; Centre for Biopharmaceutics and Pharmacokinetics, University College of Pharmaceutical Sciences, Kakatiya University, Warangal-506 009 (A.P.), India
CHANDRA MOHAN EAGA ; Centre for Biopharmaceutics and Pharmacokinetics, University College of Pharmaceutical Sciences, Kakatiya University, Warangal-506 009 (A.P.), India
ASHOK THADISHETTY ; Centre for Biopharmaceutics and Pharmacokinetics, University College of Pharmaceutical Sciences, Kakatiya University, Warangal-506 009 (A.P.), India
MADHUSUDAN RAO YAMSANI ; Centre for Biopharmaceutics and Pharmacokinetics, University College of Pharmaceutical Sciences, Kakatiya University, Warangal-506 009 (A.P.), India

Puni tekst: engleski, pdf (100 KB) str. 89-97 preuzimanja: 892* citiraj
APA 6th Edition
BANDARI, S., EAGA, C.M., THADISHETTY, A. i YAMSANI, M.R. (2010). Formulation and evaluation of multiple tablets as a biphasic gastroretentivefloating drug delivery system for fenoverine. Acta Pharmaceutica, 60 (1), 89-97. https://doi.org/10.2478/v10007-010-0001-3
MLA 8th Edition
BANDARI, SURESH, et al. "Formulation and evaluation of multiple tablets as a biphasic gastroretentivefloating drug delivery system for fenoverine." Acta Pharmaceutica, vol. 60, br. 1, 2010, str. 89-97. https://doi.org/10.2478/v10007-010-0001-3. Citirano 16.06.2019.
Chicago 17th Edition
BANDARI, SURESH, CHANDRA MOHAN EAGA, ASHOK THADISHETTY i MADHUSUDAN RAO YAMSANI. "Formulation and evaluation of multiple tablets as a biphasic gastroretentivefloating drug delivery system for fenoverine." Acta Pharmaceutica 60, br. 1 (2010): 89-97. https://doi.org/10.2478/v10007-010-0001-3
Harvard
BANDARI, S., et al. (2010). 'Formulation and evaluation of multiple tablets as a biphasic gastroretentivefloating drug delivery system for fenoverine', Acta Pharmaceutica, 60(1), str. 89-97. doi: https://doi.org/10.2478/v10007-010-0001-3
Vancouver
BANDARI S, EAGA CM, THADISHETTY A, YAMSANI MR. Formulation and evaluation of multiple tablets as a biphasic gastroretentivefloating drug delivery system for fenoverine. Acta Pharm. [Internet]. 2010 [pristupljeno 16.06.2019.];60(1):89-97. doi: https://doi.org/10.2478/v10007-010-0001-3
IEEE
S. BANDARI, C.M. EAGA, A. THADISHETTY i M.R. YAMSANI, "Formulation and evaluation of multiple tablets as a biphasic gastroretentivefloating drug delivery system for fenoverine", Acta Pharmaceutica, vol.60, br. 1, str. 89-97, 2010. [Online]. doi: https://doi.org/10.2478/v10007-010-0001-3

Sažetak
A biphasic gastroretentive drug delivery system of fenoverine was developed to maintain constant plasma concentration. The delivery system consisted of a loading-dose tablet and a floating multiple matrix tablet prepared by the direct compression process. The drug release from biphasic GRDDS in 0.1 mol L1 HCl and SGF (enzyme free) was sustained over 12 h with buoyant properties. Stability studies showed no significant change in dissolution profiles (f2 value > 50). Based on the release kinetics, it can be concluded that the floating multiple matrix tablet containing HPMC was a particularly suitable gastroretentive drug delivery system with a zero-order release profile.

Ključne riječi
biphasic release; gastroretention; multiple matrix tablet; release kinetics

Hrčak ID: 41962

URI
https://hrcak.srce.hr/41962

[hrvatski]

Posjeta: 1.140 *