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https://doi.org/10.2478/10004-1254-60-2009-1938

Urine Ochratoxin A and Sphinganine/Sphingosine Ratio in Residents of the Endemic Nephropathy Area in Croatia

Ana-Marija Domijan ; Institute for Medical Research and Occupational Health, Zagreb, Croatia
Maja Peraica ; Institute for Medical Research and Occupational Health, Zagreb, Croatia
Ksenija Markov ; Faculty of Food Technology and Biotechnology,niversity of Zagreb, Zagreb, Croatia
Radovan Fuchs ; Institute for Medical Research and Occupational Health, Zagreb, Croatia

Puni tekst: engleski, pdf (84 KB) str. 387-392 preuzimanja: 474* citiraj
APA 6th Edition
Domijan, A., Peraica, M., Markov, K. i Fuchs, R. (2009). Urine Ochratoxin A and Sphinganine/Sphingosine Ratio in Residents of the Endemic Nephropathy Area in Croatia. Arhiv za higijenu rada i toksikologiju, 60 (4), 387-392. https://doi.org/10.2478/10004-1254-60-2009-1938
MLA 8th Edition
Domijan, Ana-Marija, et al. "Urine Ochratoxin A and Sphinganine/Sphingosine Ratio in Residents of the Endemic Nephropathy Area in Croatia." Arhiv za higijenu rada i toksikologiju, vol. 60, br. 4, 2009, str. 387-392. https://doi.org/10.2478/10004-1254-60-2009-1938. Citirano 07.03.2021.
Chicago 17th Edition
Domijan, Ana-Marija, Maja Peraica, Ksenija Markov i Radovan Fuchs. "Urine Ochratoxin A and Sphinganine/Sphingosine Ratio in Residents of the Endemic Nephropathy Area in Croatia." Arhiv za higijenu rada i toksikologiju 60, br. 4 (2009): 387-392. https://doi.org/10.2478/10004-1254-60-2009-1938
Harvard
Domijan, A., et al. (2009). 'Urine Ochratoxin A and Sphinganine/Sphingosine Ratio in Residents of the Endemic Nephropathy Area in Croatia', Arhiv za higijenu rada i toksikologiju, 60(4), str. 387-392. https://doi.org/10.2478/10004-1254-60-2009-1938
Vancouver
Domijan A, Peraica M, Markov K, Fuchs R. Urine Ochratoxin A and Sphinganine/Sphingosine Ratio in Residents of the Endemic Nephropathy Area in Croatia. Arh Hig Rada Toksikol. [Internet]. 2009 [pristupljeno 07.03.2021.];60(4):387-392. https://doi.org/10.2478/10004-1254-60-2009-1938
IEEE
A. Domijan, M. Peraica, K. Markov i R. Fuchs, "Urine Ochratoxin A and Sphinganine/Sphingosine Ratio in Residents of the Endemic Nephropathy Area in Croatia", Arhiv za higijenu rada i toksikologiju, vol.60, br. 4, str. 387-392, 2009. [Online]. https://doi.org/10.2478/10004-1254-60-2009-1938

Sažetak
The most plausible theory of the aetiology of endemic nephropathy links it with exposure to nephrotoxic mycotoxin ochratoxin A (OTA). In this study, the concentration of OTA and sphinganine/sphingosine
(Sa/So) ratio, the biomarker of another nephrotoxic mycotoxin fumonisin B1 exposure, were analysed in 45 human urine samples collected in the endemic village of Kaniža in Croatia and in 18 samples from control village. Samples were collected twice from the same persons in 2000 and 2005. In both years the frequency
of OTA-positive samples was higher in Kaniža (43 % and 18 %, respectively) than in the control village (28 % and 6 %, respectively). OTA concentrations in samples collected in Kaniža were higher in 2000 than in 2005 (p<0.005). Although in both years Sa/So ratio was higher in Kaniža, the difference from the control group was not statistically signifi cant. No control sample contained OTA and had the Sa/So ratio >1 at the same time, while in Kaniža four such samples were collected in 2000 and one in 2005.

Ključne riječi
endemic nephropathy; fumonisin B1; HPLC; ochratoxin A; sphingolipids

Hrčak ID: 45370

URI
https://hrcak.srce.hr/45370

[hrvatski]

Posjeta: 1.018 *