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HYPERPROLACTINAEMIA – A RISPERIDONE SIDE-EFFECT

Tanja Grahovac ; University Psychiatric Clinic Rijeka, Clinical Hospital Centre Rijeka, Rijeka, Croatia
Klementina Ružić ; University Psychiatric Clinic Rijeka, Clinical Hospital Centre Rijeka, Rijeka, Croatia
Paola Medved ; University of Rijeka, Philosophy Faculty, Psychology Department, Rijeka, Croatia
Aristea Pavešić-Radonja ; University Psychiatric Clinic Rijeka, Clinical Hospital Centre Rijeka, Rijeka, Croatia
Eizabeta Dadić-Hero ; Community Primary Health Centre, Primorsko-goranska county, Rijeka, Croatia


Puni tekst: engleski pdf 212 Kb

str. 120-122

preuzimanja: 721

citiraj


Sažetak

A 47 year old patient has been treated for psychotic depression for the last 5 years. The illness began manifesting through the
symptoms of depressive thoughts, intrapsychic tension, projectivity, derealisation phenomena and pre-psychotic fears. She was
treated with a combination of antidepressives, anxiolitics and hypnotics in ambulatory conditions. The therapy applied did not obtain
the effects expected due to which an atypical antipsychotic was administered subsequently – risperidone, a 2 mg dose in the evening.
After commencing the antipsychotic treatment, the symptoms started to weaken and a steady remission was obtained.
Two years after a regular risperidone administration (in combination with fluoxetine, alprazolam and flurazepam) the patient
reported some „bleeding“ in October 2006. Hormonal blood tests were performed and high prolactin values were registered (2567.0 mIJ/L),due to which a gradual risperidone retractement was indicated. Medicamentous hyperprolactinaemia is a well known side
effect of risperidone. A gradual risperidone retractement lead to a lowered and normal prolactin level within a month.

Ključne riječi

psychotic depression; risperidone; hyperprolactinaemia

Hrčak ID:

48663

URI

https://hrcak.srce.hr/48663

Datum izdavanja:

10.2.2010.

Posjeta: 1.178 *