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Arhiv za higijenu rada i toksikologiju, Vol. 61 No. 1, 2010.

Pregledni rad
https://doi.org/10.2478/10004-1254-61-2010-1942

Allergotoxicology: Research of Pollutant Influence on the Development of Allergic Reactions

Božica Kanceljak-Macan ; Institut za medicinska istraživanja i medicinu rada, Zagreb, Hrvatska

Puni tekst: hrvatski, pdf (127 KB) str. 85-93 preuzimanja: 518* citiraj
APA 6th Edition
Kanceljak-Macan, B. (2010). Alergotoksikologija: istraživanja utjecaja polutanata na pojavu alergijskih reakcija. Arhiv za higijenu rada i toksikologiju, 61 (1), 85-93. https://doi.org/10.2478/10004-1254-61-2010-1942
MLA 8th Edition
Kanceljak-Macan, Božica. "Alergotoksikologija: istraživanja utjecaja polutanata na pojavu alergijskih reakcija." Arhiv za higijenu rada i toksikologiju, vol. 61, br. 1, 2010, str. 85-93. https://doi.org/10.2478/10004-1254-61-2010-1942. Citirano 20.02.2019.
Chicago 17th Edition
Kanceljak-Macan, Božica. "Alergotoksikologija: istraživanja utjecaja polutanata na pojavu alergijskih reakcija." Arhiv za higijenu rada i toksikologiju 61, br. 1 (2010): 85-93. https://doi.org/10.2478/10004-1254-61-2010-1942
Harvard
Kanceljak-Macan, B. (2010). 'Alergotoksikologija: istraživanja utjecaja polutanata na pojavu alergijskih reakcija', Arhiv za higijenu rada i toksikologiju, 61(1), str. 85-93. doi: https://doi.org/10.2478/10004-1254-61-2010-1942
Vancouver
Kanceljak-Macan B. Alergotoksikologija: istraživanja utjecaja polutanata na pojavu alergijskih reakcija. Arh Hig Rada Toksikol. [Internet]. 2010 [pristupljeno 20.02.2019.];61(1):85-93. doi: https://doi.org/10.2478/10004-1254-61-2010-1942
IEEE
B. Kanceljak-Macan, "Alergotoksikologija: istraživanja utjecaja polutanata na pojavu alergijskih reakcija", Arhiv za higijenu rada i toksikologiju, vol.61, br. 1, str. 85-93, 2010. [Online]. doi: https://doi.org/10.2478/10004-1254-61-2010-1942

Sažetak
Allergotoxicology studies the infl uence of pollutants on the development of allergic reactions and diseases. At the beginning, the research was focused on outdoor air pollutants, while recently it turns to the indoor environment, mainly because people this is where people spend most of their time. Air pollutants may be solid, soluble, or gaseous particles in nature, and they can differ in size, structure, and sources. Pollutants can be of biological or nonbiological origin. Currently interesting air pollutants include particulate matter, ozone, nitrogen oxides, and bioaerosols. The mechanisms of pollutant activity depend on the particle size, solubility, site of deposition, and specifi c chemical properties. Recent studies have shown that different pollutants provoke different immunological and nonimmunological responses in exposed persons. Interaction between air pollutants and allergens can take place outside the exposed person i.e. with allergen itself, or inside the organism on mucous membranes and skin. Pollutants may be the carriers of allergens and may exacerbate allergic reactions and diseases. This review presents recent views about the mechanisms of pollutant activity on allergens and immune system response in exposed persons, based on epidemiological population studies, clinical studies of exposure under controlled conditions, and experimental tests in vitro and in vivo.

Ključne riječi
air polluants; allergens; asthma; bioaerosols; IgE antibody; LLNA; particulate matter; pollen allergy; protein-hapten conjugates

Hrčak ID: 49023

URI
https://hrcak.srce.hr/49023

[hrvatski]

Posjeta: 858 *