hrcak mascot   Srce   HID

Izvorni znanstveni članak

IS THERE A CORTICAL BLOOD FLOW REDISTRIBUTION PATTERN RELATED WITH PERSEVERATIVE ERROR IN SCHIZOPHRENIA?

Felipe Ortuño ; Depart. of Psychiatry and Med. Psychology, University Clinic, University of Navarra College of Medicine, Pamplona, Spain
Javier Arbizu ; Department of Nuclear Medicine, University Clinic, University of Navarra College of Medicine, Pamplona, Spain
Cesar A. Soutullo ; Depart. of Psychiatry and Med. Psychology, University Clinic, University of Navarra College of Medicine, Pamplona, Spain
Raphael M. Bonelli ; Department of Psychiatry, Graz Medical University, A-8036-Graz, Austria

Puni tekst: engleski, pdf (347 KB) str. 283-289 preuzimanja: 454* citiraj
APA 6th Edition
Ortuño, F., Arbizu, J., Soutullo, C.A. i Bonelli, R.M. (2009). IS THERE A CORTICAL BLOOD FLOW REDISTRIBUTION PATTERN RELATED WITH PERSEVERATIVE ERROR IN SCHIZOPHRENIA?. Psychiatria Danubina, 21 (3), 283-289. Preuzeto s https://hrcak.srce.hr/49211
MLA 8th Edition
Ortuño, Felipe, et al. "IS THERE A CORTICAL BLOOD FLOW REDISTRIBUTION PATTERN RELATED WITH PERSEVERATIVE ERROR IN SCHIZOPHRENIA?." Psychiatria Danubina, vol. 21, br. 3, 2009, str. 283-289. https://hrcak.srce.hr/49211. Citirano 07.04.2020.
Chicago 17th Edition
Ortuño, Felipe, Javier Arbizu, Cesar A. Soutullo i Raphael M. Bonelli. "IS THERE A CORTICAL BLOOD FLOW REDISTRIBUTION PATTERN RELATED WITH PERSEVERATIVE ERROR IN SCHIZOPHRENIA?." Psychiatria Danubina 21, br. 3 (2009): 283-289. https://hrcak.srce.hr/49211
Harvard
Ortuño, F., et al. (2009). 'IS THERE A CORTICAL BLOOD FLOW REDISTRIBUTION PATTERN RELATED WITH PERSEVERATIVE ERROR IN SCHIZOPHRENIA?', Psychiatria Danubina, 21(3), str. 283-289. Preuzeto s: https://hrcak.srce.hr/49211 (Datum pristupa: 07.04.2020.)
Vancouver
Ortuño F, Arbizu J, Soutullo CA, Bonelli RM. IS THERE A CORTICAL BLOOD FLOW REDISTRIBUTION PATTERN RELATED WITH PERSEVERATIVE ERROR IN SCHIZOPHRENIA?. Psychiatria Danubina [Internet]. 2009 [pristupljeno 07.04.2020.];21(3):283-289. Dostupno na: https://hrcak.srce.hr/49211
IEEE
F. Ortuño, J. Arbizu, C.A. Soutullo i R.M. Bonelli, "IS THERE A CORTICAL BLOOD FLOW REDISTRIBUTION PATTERN RELATED WITH PERSEVERATIVE ERROR IN SCHIZOPHRENIA?", Psychiatria Danubina, vol.21, br. 3, str. 283-289, 2009. [Online]. Dostupno na: https://hrcak.srce.hr/49211. [Citirano: 07.04.2020.]

Sažetak
Background: We studied relative cortical blood flow (relCBF) patterns
associated to correct performance (CP) and perseverative error (PE) during Wisconsin Card Sorting Test (WCST) execution, in controls and patients with schizophrenia.
Subjects and methods: relCBF (regional cortical blood flow (rCBF) / whole cortex blood flow) of 10 well defined cortical regions was measured in 18 patients with schizophrenia and 13 healthy controls by a Technetium – 99 – HMPAO – SPECT, at rest and while they performed WCST.
Results: Patients made significantly more PE than controls during WCST performance. In patients, we found a significant correlation between PE and relCBF in right occipital cortex. In controls, we found a significant correlation between CP and relCBF of several cortical regions during WCST execution: left orbitofrontal cortex and left global frontal cortex positively and parietal bilateral cortex
negatively. PE was inversely correlated with relCBF in left temporal cortex.
Conclusions: Successful WCST performance is associated to a high left frontal activity in controls but not in patients. The severity of PE during WCST performance is associated to a low left frontal-temporal activity in controls and to a high right parietal-occipital activity in schizophrenia. This may represent a cortical activity redistribution pattern related to perseveration in schizophrenia.

Ključne riječi
schizophrenia; Wisconsin Card Sorting Test; SPECT; perseveration; prefrontal cortex

Hrčak ID: 49211

URI
https://hrcak.srce.hr/49211

Posjeta: 674 *