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LABIAL AGGLUTINATION AND INFECTION IN PREPUBERTAL GIRLS

Nives Šikanić Dugić ; Klinika za dječje bolesti Zagreb
Nives Pustišek ; Klinika za dječje bolesti Zagreb
Vlasta Hiršl Hećej ; Klinika za dječje bolesti Zagreb
Amarela Lukić Grlić ; Klinika za dječje bolesti Zagreb



Sažetak

Objectives: To assess the correlation of previous infections with the frequency of labial agglutination, to confirm the effectiveness of oestrogen therapy and the frequency of positive microbiological swabs after treatment.
Methods: The study included 88 girls aged from 3 months to 10 years who have been examined at the Gynaecological outpatient unit of Children's Hospital Zagreb from 2005-2007. Anamnestic data about previous infections were obtained from the parents. All girls were treated with an oestradiol cream twice a day. The patients were then re-examined 2 weeks and /or 4 weeks later, if necessary. After the treatment, vaginal and vulvar smears were taken for microbiological analysis.
Results: Twenty-eight (31.8%) girls were lost to follow up. Out of 60 girls in 27 (45%) girls we learned about a previous respiratory or urinary infection in the 3 months before our exam. 45/60 (60%) girls presented with complete agglutination, but without urine disturbances and 15/60 (25%) had partial fusion. After 2 weeks of treatment we found complete resolution in 16/60 (26.7%) cases, after 4 weeks in 30/60 (50%) cases, and after 4-6 weeks of local hormonal treatment in 14/60 (23.3%) cases. Out of 60 study patients’ culture in 27 (45 %) the causative agents were isolated from the vaginal culture. Agglutination subsequently recurred in 20/60 children (33. 3%), mostly in association with respiratory infection
Conclusion: Topical oestrogen application is the method of choice in the treatment of labial agglutination, but for at least 4 weeks of application. Recurrence of agglutination is common and mostly associated with infection. It could be reduced by application of a lubricant to lysed surfaces for as long as 6 months after lysis and at the time of infection.

Ključne riječi

Descriptors: VULVA; AGGLUTINATION; INFECTION

Hrčak ID:

49755

URI

https://hrcak.srce.hr/49755

Datum izdavanja:

18.3.2010.

Podaci na drugim jezicima: hrvatski

Posjeta: 2.171 *