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Lymphomatoid Granulomatosis in a 23-year-old Man – Cytological and Histological Typing and Rapid Response to Steroid and Cyclophosphamide Combination Therapy

Neven Rakušić ; University Hospital for Lung Diseases »Jordanovac«, Zagreb, Croatia
Diana Krmpotić ; University Hospital for Lung Diseases »Jordanovac«, Zagreb, Croatia
Ana Hećimović ; University Hospital for Lung Diseases »Jordanovac«, Zagreb, Croatia
Zagorka Boras ; University Hospital for Lung Diseases »Jordanovac«, Zagreb, Croatia
Božica Vrabec-Branica ; University Hospital for Lung Diseases »Jordanovac«, Zagreb, Croatia
Sonja Džebro
Nevena Rakušić ; University of Zagreb, School of Medicine, Zagreb, Croatia
Tomislav Rešković ; University of Rijeka, School of Medicine, Rijeka, Croatia
Nika Rakušić ; University of Rijeka, School of Medicine, Rijeka, Croatia

Puni tekst: engleski, pdf (319 KB) str. 279-283 preuzimanja: 376* citiraj
APA 6th Edition
Rakušić, N., Krmpotić, D., Hećimović, A., Boras, Z., Vrabec-Branica, B., Džebro, S., ... Rakušić, N. (2010). Lymphomatoid Granulomatosis in a 23-year-old Man – Cytological and Histological Typing and Rapid Response to Steroid and Cyclophosphamide Combination Therapy. Collegium antropologicum, 34 (1), 279-283. Preuzeto s https://hrcak.srce.hr/51279
MLA 8th Edition
Rakušić, Neven, et al. "Lymphomatoid Granulomatosis in a 23-year-old Man – Cytological and Histological Typing and Rapid Response to Steroid and Cyclophosphamide Combination Therapy." Collegium antropologicum, vol. 34, br. 1, 2010, str. 279-283. https://hrcak.srce.hr/51279. Citirano 02.06.2020.
Chicago 17th Edition
Rakušić, Neven, Diana Krmpotić, Ana Hećimović, Zagorka Boras, Božica Vrabec-Branica, Sonja Džebro, Nevena Rakušić, Tomislav Rešković i Nika Rakušić. "Lymphomatoid Granulomatosis in a 23-year-old Man – Cytological and Histological Typing and Rapid Response to Steroid and Cyclophosphamide Combination Therapy." Collegium antropologicum 34, br. 1 (2010): 279-283. https://hrcak.srce.hr/51279
Harvard
Rakušić, N., et al. (2010). 'Lymphomatoid Granulomatosis in a 23-year-old Man – Cytological and Histological Typing and Rapid Response to Steroid and Cyclophosphamide Combination Therapy', Collegium antropologicum, 34(1), str. 279-283. Preuzeto s: https://hrcak.srce.hr/51279 (Datum pristupa: 02.06.2020.)
Vancouver
Rakušić N, Krmpotić D, Hećimović A, Boras Z, Vrabec-Branica B, Džebro S i sur. Lymphomatoid Granulomatosis in a 23-year-old Man – Cytological and Histological Typing and Rapid Response to Steroid and Cyclophosphamide Combination Therapy. Collegium antropologicum [Internet]. 2010 [pristupljeno 02.06.2020.];34(1):279-283. Dostupno na: https://hrcak.srce.hr/51279
IEEE
N. Rakušić, et al., "Lymphomatoid Granulomatosis in a 23-year-old Man – Cytological and Histological Typing and Rapid Response to Steroid and Cyclophosphamide Combination Therapy", Collegium antropologicum, vol.34, br. 1, str. 279-283, 2010. [Online]. Dostupno na: https://hrcak.srce.hr/51279. [Citirano: 02.06.2020.]

Sažetak
Lymphomatoid granulomatosis (LG) is currently called as extranodal angiocentric and angiodestructive immunoproliferative disorder with various degrees of histological differentiation and disease severity. Histological grading and clinical manifestations are due to number of atypical large EBV+ B-lymphatic cells. We report the case of a 23-year-old man clinically presented with fever, sweating, and physical intolerance, and bilateral pulmonary infiltrates of nodular type and destructive changes on the chest X-ray, previously treated with antituberculotics for 1.5 month. As the disease showed progression, diagnostic procedures extended to transbronchial lung biopsy and percutaneous fine needle aspiration with cytological and histological analysis of collected specimens, all being not conclusive enough. LG was confirmed by open lung biopsy, followed by induction of corticosteroids and cyclophosphamide therapy. Very good clinical, functional and radiomorphologic improvement was achieved in a few weeks, and remission of disease maintained in long term follow-up.

Ključne riječi
lymphomatoid granulomatosis; pulmonary nodular infiltrates; open lung biopsy; EBV+ B-lymphatic cells

Hrčak ID: 51279

URI
https://hrcak.srce.hr/51279

Posjeta: 694 *