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Multiple Primary Melanoma: Epidemiological and Prognostic Implications; Analysis of 36 Cases

Marija Buljan ; Department of Dermatology and Venereology, University Hospital »Sestre Milosrdnice«, Zagreb, Croatia
Mirna Šitum ; Department of Dermatology and Venereology, University Hospital »Sestre Milosrdnice«, Zagreb, Croatia
Željana Bolanča ; Department of Dermatology and Venereology, University Hospital »Sestre Milosrdnice«, Zagreb, Croatia
Maja Vurnek Živković ; Department of Dermatology and Venereology, University Hospital »Sestre Milosrdnice«, Zagreb, Croatia
Liborija Lugović Mihić ; Department of Dermatology and Venereology, University Hospital »Sestre Milosrdnice«, Zagreb, Croatia

Puni tekst: engleski, pdf (62 KB) str. 131-134 preuzimanja: 419* citiraj
APA 6th Edition
Buljan, M., Šitum, M., Bolanča, Ž., Vurnek Živković, M. i Lugović Mihić, L. (2010). Multiple Primary Melanoma: Epidemiological and Prognostic Implications; Analysis of 36 Cases. Collegium antropologicum, 34 supplement 2 (2), 131-134. Preuzeto s https://hrcak.srce.hr/51644
MLA 8th Edition
Buljan, Marija, et al. "Multiple Primary Melanoma: Epidemiological and Prognostic Implications; Analysis of 36 Cases." Collegium antropologicum, vol. 34 supplement 2, br. 2, 2010, str. 131-134. https://hrcak.srce.hr/51644. Citirano 13.06.2021.
Chicago 17th Edition
Buljan, Marija, Mirna Šitum, Željana Bolanča, Maja Vurnek Živković i Liborija Lugović Mihić. "Multiple Primary Melanoma: Epidemiological and Prognostic Implications; Analysis of 36 Cases." Collegium antropologicum 34 supplement 2, br. 2 (2010): 131-134. https://hrcak.srce.hr/51644
Harvard
Buljan, M., et al. (2010). 'Multiple Primary Melanoma: Epidemiological and Prognostic Implications; Analysis of 36 Cases', Collegium antropologicum, 34 supplement 2(2), str. 131-134. Preuzeto s: https://hrcak.srce.hr/51644 (Datum pristupa: 13.06.2021.)
Vancouver
Buljan M, Šitum M, Bolanča Ž, Vurnek Živković M, Lugović Mihić L. Multiple Primary Melanoma: Epidemiological and Prognostic Implications; Analysis of 36 Cases. Collegium antropologicum [Internet]. 2010 [pristupljeno 13.06.2021.];34 supplement 2(2):131-134. Dostupno na: https://hrcak.srce.hr/51644
IEEE
M. Buljan, M. Šitum, Ž. Bolanča, M. Vurnek Živković i L. Lugović Mihić, "Multiple Primary Melanoma: Epidemiological and Prognostic Implications; Analysis of 36 Cases", Collegium antropologicum, vol.34 supplement 2, br. 2, str. 131-134, 2010. [Online]. Dostupno na: https://hrcak.srce.hr/51644. [Citirano: 13.06.2021.]

Sažetak
Patients who are already diagnosed with cutaneous melanoma are at increased risk of developing another primary melanoma. The occurrence of multiple primary melanoma is a rare phenomenon, varying in frequency, with an estimated incidence ranging from 0.2% to 8.6%. The authors are presenting data on the patients with multiple primary melanoma from the Croatian Referral Melanoma Centre. The clinical, histological and epidemiological characteristics of 36 (3.6%) patients, identified from 991 patients with histologically confirmed melanoma, are analyzed in this study. Twenty-eight of the patients (78%) had two primary melanomas, six had three melanomas (16,7%) and two (5,6%) had four melanomas. Diagnosis was established synchronously in 11 patients (30%) and, in the rest of the patients, time interval between the diagnosis of the first and second melanoma varied from 1 month to the longest interval of 16 years. However, the majority of subsequent melanomas were removed within 2 years of the initial operation. The mean Breslow’s thickness of the first melanoma was significantly higher than the mean Breslow’s thickness of the second primary melanoma. The proportion of in situ to invasive melanomas was greater for the second melanomas compared with the first melanomas. Therefore, we emphasize the importance of regular follow-up as well as the education in regular self-skin examinations in melanoma patients in order to detect subsequent primary melanomas in the early phase.

Ključne riječi
melanoma; multiple primary melanoma; follow up; patient education

Hrčak ID: 51644

URI
https://hrcak.srce.hr/51644

Posjeta: 685 *