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Professional paper

Transrectal Sonography in Prostate Cancer Detection – Our 25 Years Experience of Implementation

Antun Maričić ; Department of Urology, University Hospital of Rijeka, Rijeka, Croatia
Maksim Valenčić ; Department of Urology, University Hospital of Rijeka, Rijeka, Croatia
Stanislav Sotošek ; Department of Urology, University Hospital of Rijeka, Rijeka, Croatia
Romano Oguić ; Department of Urology, University Hospital of Rijeka, Rijeka, Croatia
Aldo Ivančić ; Department of Surgery, University Hospital of Rijeka, Rijeka, Croatia
Juraj Ahel ; Department of Urology, University Hospital of Rijeka, Rijeka, Croatia

Fulltext: english, pdf (120 KB) pages 239-242 downloads: 288* cite
APA 6th Edition
Maričić, A., Valenčić, M., Sotošek, S., Oguić, R., Ivančić, A. & Ahel, J. (2010). Transrectal Sonography in Prostate Cancer Detection – Our 25 Years Experience of Implementation. Collegium antropologicum, 34 supplement 2 (2), 239-242. Retrieved from https://hrcak.srce.hr/51666
MLA 8th Edition
Maričić, Antun, et al. "Transrectal Sonography in Prostate Cancer Detection – Our 25 Years Experience of Implementation." Collegium antropologicum, vol. 34 supplement 2, no. 2, 2010, pp. 239-242. https://hrcak.srce.hr/51666. Accessed 22 Oct. 2020.
Chicago 17th Edition
Maričić, Antun, Maksim Valenčić, Stanislav Sotošek, Romano Oguić, Aldo Ivančić and Juraj Ahel. "Transrectal Sonography in Prostate Cancer Detection – Our 25 Years Experience of Implementation." Collegium antropologicum 34 supplement 2, no. 2 (2010): 239-242. https://hrcak.srce.hr/51666
Harvard
Maričić, A., et al. (2010). 'Transrectal Sonography in Prostate Cancer Detection – Our 25 Years Experience of Implementation', Collegium antropologicum, 34 supplement 2(2), pp. 239-242. Available at: https://hrcak.srce.hr/51666 (Accessed 22 October 2020)
Vancouver
Maričić A, Valenčić M, Sotošek S, Oguić R, Ivančić A, Ahel J. Transrectal Sonography in Prostate Cancer Detection – Our 25 Years Experience of Implementation. Collegium antropologicum [Internet]. 2010 [cited 2020 October 22];34 supplement 2(2):239-242. Available from: https://hrcak.srce.hr/51666
IEEE
A. Maričić, M. Valenčić, S. Sotošek, R. Oguić, A. Ivančić and J. Ahel, "Transrectal Sonography in Prostate Cancer Detection – Our 25 Years Experience of Implementation", Collegium antropologicum, vol.34 supplement 2, no. 2, pp. 239-242, 2010. [Online]. Available: https://hrcak.srce.hr/51666. [Accessed: 22 October 2020]

Abstracts
Prostate cancer is a leading public health problem of male population in developed countries. Gold standard for prostate cancer diagnosis is true cut biopsy guided by transrectal ultrasound1–5. Aim of this study was to determine sensitivity, specificity, accuracy, positive and negative predictive value of transrectal sonography (TRUS) in prostate cancer detection. The analysis was made for two time periods, before and after routine implementation of prostate specific antigen (PSA) in prostate cancer diagnostics. From 1984 to 1993 TRUS guided prostate biopsy was performed in 564, and from 1994 to 2008 in 5678 patients. In the second period PSA was routinely used in prostate cancer diagnostics. In the first period by TRUS we have made an exact diagnosis of prostate cancer in 18.97% of patients what was confirmed by biopsy. 4.61% ware false positive and 11.34% ware false negative. In the second period prostate cancer was recognized in 30.34% of patients, confirmed by biopsy. False positive cases ware 6.11% and false negative 29.31%. Sensitivity of transrectal sonography in the first period was 62.57%, specificity 94.2%, accuracy 86.2%, positive predictive value 80.45% and negative predictive value 87.72%. In the second period sensitivity was 50.87%, specificity 91.93%, accuracy 73.84%, positive predictive value 83.24% and negative predictive value 70.39%. Based on our experience we can conclude that prostate cancer is mostly found in the peripheral zone. Smaller tumors are hipoechoic and bigger tumors are hiperechoic. Prostate cancer lesions are impossible to differentiate from chronic prostatitis only by TRUS. Implementation of PSA has significantly decrease sensitivity, accuracy and negative predictive value of TRUS in prostate cancer detection. TRUS guided true cut biopsy is a gold standard in prostate cancer diagnostics.

Keywords
prostate cancer; sonography; biopsy

Hrčak ID: 51666

URI
https://hrcak.srce.hr/51666

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