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Acta Pharmaceutica, Vol. 60 No. 2, 2010.

Kratko priopćenje
https://doi.org/10.2478/v10007-010-0018-7

Chemical and biological investigations of Delonix regia (Bojer ex Hook.) Raf.

Israt Jahan ; Department of Clinical Pharmacy and Pharmacology, Faculty of Pharmacy, University of Dhaka, Dhaka-1000, Bangladesh
Mohammad S. Rahman ; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Dhaka, Dhaka-1000, Bangladesh
Mohammed Z. Rahman ; Department of Pharmacy, The University of Asia Pacific, Dhaka-1209, Bangladesh
Mohammad A. Kaisar ; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Dhaka, Dhaka-1000, Bangladesh
Mohammad S. Islam ; Department of Clinical Pharmacy and Pharmacology, Faculty of Pharmacy, University of Dhaka, Dhaka-1000, Bangladesh
Abdul Wahab ; Department of Skin & Veneral Diseases, Bangabandhu Sheikh Mujib Medical University, Shahbag, Dhaka-1000, Bangladesh
Mohammad A. Rashid ; Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Dhaka, Dhaka-1000, Bangladesh

Puni tekst: hrvatski, pdf (79 KB) str. 207-215 preuzimanja: 1.079* citiraj
APA 6th Edition
Jahan, I., Rahman, M.S., Rahman, M.Z., Kaisar, M.A., Islam, M.S., Wahab, A. i Rashid, M.A. (2010). Kemijsko i biološko ispitivanje biljke Delonix regia (Bojer ex Hook.) Raf.. Acta Pharmaceutica, 60 (2), 207-215. https://doi.org/10.2478/v10007-010-0018-7
MLA 8th Edition
Jahan, Israt, et al. "Kemijsko i biološko ispitivanje biljke Delonix regia (Bojer ex Hook.) Raf.." Acta Pharmaceutica, vol. 60, br. 2, 2010, str. 207-215. https://doi.org/10.2478/v10007-010-0018-7. Citirano 21.02.2019.
Chicago 17th Edition
Jahan, Israt, Mohammad S. Rahman, Mohammed Z. Rahman, Mohammad A. Kaisar, Mohammad S. Islam, Abdul Wahab i Mohammad A. Rashid. "Kemijsko i biološko ispitivanje biljke Delonix regia (Bojer ex Hook.) Raf.." Acta Pharmaceutica 60, br. 2 (2010): 207-215. https://doi.org/10.2478/v10007-010-0018-7
Harvard
Jahan, I., et al. (2010). 'Kemijsko i biološko ispitivanje biljke Delonix regia (Bojer ex Hook.) Raf.', Acta Pharmaceutica, 60(2), str. 207-215. doi: https://doi.org/10.2478/v10007-010-0018-7
Vancouver
Jahan I, Rahman MS, Rahman MZ, Kaisar MA, Islam MS, Wahab A i sur. Kemijsko i biološko ispitivanje biljke Delonix regia (Bojer ex Hook.) Raf.. Acta Pharm. [Internet]. 2010 [pristupljeno 21.02.2019.];60(2):207-215. doi: https://doi.org/10.2478/v10007-010-0018-7
IEEE
I. Jahan, et al., "Kemijsko i biološko ispitivanje biljke Delonix regia (Bojer ex Hook.) Raf.", Acta Pharmaceutica, vol.60, br. 2, str. 207-215, 2010. [Online]. doi: https://doi.org/10.2478/v10007-010-0018-7

Sažetak
In this study five compounds, lupeol (1), epilupeol (2), β-sitosterol (3), stigmasterol (4) and p-methoxybenzaldehyde (5) were isolated from the petroleum ether and dichloromethane fractions of a methanolic extract of the stem bark of Delonix regia. Antimicrobial screening of the different extracts (15 μg mm2) was conducted by disc diffusion method. The zones of inhibition demonstrated by the petroleum ether, carbon tetrachloride and dichloromethane fractions ranged from 914 mm, 1113 mm and 920 mm, respectively, compared to kanamycin standard with the zone of inhibition of 2025 mm. In brine shrimp lethality bioassay, the carbon tetrachloride soluble materials demonstrated the highest toxicity with LC50 of 0.83 μg mL1, while petroleum ether and dichloromethane soluble partitionates of the methanolic extract revealed LC50 of 14.94 and 3.29 μg mL1, respectively, in comparison with standard vincristine sulphate with LC50 of 0.812 μg mL1. This is the first report on compounds separation from D. regia, their antimicrobial activity and cytotoxicity.

Ključne riječi
Delonix regia (Fabaceae); methanolic extract; antimicrobial activity; brine shrimp lethality

Hrčak ID: 52252

URI
https://hrcak.srce.hr/52252

[hrvatski]

Posjeta: 1.379 *