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The Effectiveness of a 40-year Long Iodine Prophylaxis in Endemic Goitre Region of Grobnik, Croatia

Željka Crnčević-Orlić
Alen Ružić
Koraljka Rajković
Miljenko Kapović

Puni tekst: engleski, pdf (119 KB) str. 509-513 preuzimanja: 420* citiraj
APA 6th Edition
Crnčević-Orlić, Ž., Ružić, A., Rajković, K. i Kapović, M. (2005). The Effectiveness of a 40-year Long Iodine Prophylaxis in Endemic Goitre Region of Grobnik, Croatia. Collegium antropologicum, 29 (2), 509-513. Preuzeto s https://hrcak.srce.hr/5229
MLA 8th Edition
Crnčević-Orlić, Željka, et al. "The Effectiveness of a 40-year Long Iodine Prophylaxis in Endemic Goitre Region of Grobnik, Croatia." Collegium antropologicum, vol. 29, br. 2, 2005, str. 509-513. https://hrcak.srce.hr/5229. Citirano 05.12.2021.
Chicago 17th Edition
Crnčević-Orlić, Željka, Alen Ružić, Koraljka Rajković i Miljenko Kapović. "The Effectiveness of a 40-year Long Iodine Prophylaxis in Endemic Goitre Region of Grobnik, Croatia." Collegium antropologicum 29, br. 2 (2005): 509-513. https://hrcak.srce.hr/5229
Harvard
Crnčević-Orlić, Ž., et al. (2005). 'The Effectiveness of a 40-year Long Iodine Prophylaxis in Endemic Goitre Region of Grobnik, Croatia', Collegium antropologicum, 29(2), str. 509-513. Preuzeto s: https://hrcak.srce.hr/5229 (Datum pristupa: 05.12.2021.)
Vancouver
Crnčević-Orlić Ž, Ružić A, Rajković K, Kapović M. The Effectiveness of a 40-year Long Iodine Prophylaxis in Endemic Goitre Region of Grobnik, Croatia. Collegium antropologicum [Internet]. 2005 [pristupljeno 05.12.2021.];29(2):509-513. Dostupno na: https://hrcak.srce.hr/5229
IEEE
Ž. Crnčević-Orlić, A. Ružić, K. Rajković i M. Kapović, "The Effectiveness of a 40-year Long Iodine Prophylaxis in Endemic Goitre Region of Grobnik, Croatia", Collegium antropologicum, vol.29, br. 2, str. 509-513, 2005. [Online]. Dostupno na: https://hrcak.srce.hr/5229. [Citirano: 05.12.2021.]

Sažetak
The region of Grobnik, in the north west of Croatia, 15 km away from the Adriatic coast and 400 meters above the sea level, used to be known as a centre of endemic goitre. Iodine prophylaxis of 10 mg KJ added per kilo salt started in Croatia during the year 1953 and it was increased to 25 mg KJ per kilo in 1996. During 1961, the prevalence of goiter among Grobnik school children was 63%, while in the adult population it was 34%. In 1981, 18% of goitrous school children and 11% of goitrous adults were found in the same region, which shows the fall in goitre prevalence in the twenty-year period, from a severe to a mild one. The aim of this study was to estimate the effectiveness of iodine prophylaxis in goitre eradication and to compare the obtained results to those found in the same region 20 and 40 years ago, namely, in 1961 and 1981. The research was conducted in 2001. We examined 472 Grobnik inhabitants, 378 children (196 girls and 182 boys, aged 7–15 years) and 94 adults. Regarding their size thyroid glands were graded according to WHO and PAHO classification. Data regarding lifestyles and health conditions were collected by individual and family questionnaires. The prevalence of goitre in 2001 was 6.6% in school children and 6.4% in adults. In relation to 1981, we found a statistically significant fall of goitre in school children at the level of p<0.01 (x2=23.65), but the prevalence change was not statistically significant in adults (p>0.01, x2=1.419). The frequency of thyroid gland hereditary diseases in native inhabitants was high, 11.7%. There were no statistically significant differences in the prevalence of goitre
or thyroid hereditary diseases between groups of native and newcomers’ children. According to our results, in the year 2001 the area of Grobnik was still was a region of a mildly expressed endemic goitre. This study presents final results of a 40-year long follow up of endemic goitre eradication, demonstrating the long-term effectiveness of iodine prophylaxis.

Ključne riječi
goitre; endemic; epidemiology; iodine prophylaxis; Grobnik; Croatia

Hrčak ID: 5229

URI
https://hrcak.srce.hr/5229

Posjeta: 718 *