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Croatica Chemica Acta, Vol.79 No.3 Studeni 2006.

Izvorni znanstveni članak

Alpha-melanotropin Peptide: Structure and Ligand–Receptor Recognition

Karlo Houra
Nikola Štambuk
Paško Konjevoda
Alenka Boban-Blagaić
Tomislav Bruketa
Biserka Pokrić

Puni tekst: engleski, pdf (99 KB) str. 379-383 preuzimanja: 618* citiraj
APA 6th Edition
Houra, K., Štambuk, N., Konjevoda, P., Boban-Blagaić, A., Bruketa, T. i Pokrić, B. (2006). Alpha-melanotropin Peptide: Structure and Ligand–Receptor Recognition. Croatica Chemica Acta, 79 (3), 379-383. Preuzeto s https://hrcak.srce.hr/5630
MLA 8th Edition
Houra, Karlo, et al. "Alpha-melanotropin Peptide: Structure and Ligand–Receptor Recognition." Croatica Chemica Acta, vol. 79, br. 3, 2006, str. 379-383. https://hrcak.srce.hr/5630. Citirano 20.11.2018.
Chicago 17th Edition
Houra, Karlo, Nikola Štambuk, Paško Konjevoda, Alenka Boban-Blagaić, Tomislav Bruketa i Biserka Pokrić. "Alpha-melanotropin Peptide: Structure and Ligand–Receptor Recognition." Croatica Chemica Acta 79, br. 3 (2006): 379-383. https://hrcak.srce.hr/5630
Harvard
Houra, K., et al. (2006). 'Alpha-melanotropin Peptide: Structure and Ligand–Receptor Recognition', Croatica Chemica Acta, 79(3), str. 379-383. Preuzeto s: https://hrcak.srce.hr/5630 (Datum pristupa: 20.11.2018.)
Vancouver
Houra K, Štambuk N, Konjevoda P, Boban-Blagaić A, Bruketa T, Pokrić B. Alpha-melanotropin Peptide: Structure and Ligand–Receptor Recognition. Croatica Chemica Acta [Internet]. 2006 [pristupljeno 20.11.2018.];79(3):379-383. Dostupno na: https://hrcak.srce.hr/5630
IEEE
K. Houra, N. Štambuk, P. Konjevoda, A. Boban-Blagaić, T. Bruketa i B. Pokrić, "Alpha-melanotropin Peptide: Structure and Ligand–Receptor Recognition", Croatica Chemica Acta, vol.79, br. 3, str. 379-383, 2006. [Online]. Dostupno na: https://hrcak.srce.hr/5630. [Citirano: 20.11.2018.]

Sažetak
The hydropathic profile, secondary structure, epitope and binding site of the a-melanotropin molecule were investigated. It was shown that the standard algorithm according to Kyte and Doolittle may be combined with complex methods of the secondary structure prediction to extract the information relevant for the epitope location and modeling. The binding ligand-receptor motifs of the hormone were investigated by means of the SSpro8 method. The Molecular Recognition Theory combined with an NCBInr protein database search was applied to find the possible paratope (receptor) structures for the predicted a-melanotropin epitope (ligand). The described concept constitutes a useful and simple set of procedures for deriving new biologically active peptides and antibodies and also for performing modulation of peptide-receptor interaction.

Ključne riječi
alpha-melanotropin; protein structure; ligand; receptor; recognition

Hrčak ID: 5630

URI
https://hrcak.srce.hr/5630

Posjeta: 883 *