Izvorni znanstveni članak

Reaction of bone tissue to cemented total hip replacement in sheep

Daroslav Franka ; Veterinary Clinic, Trnava, Slovak Republic
Valent Ledecký ; Department of Surgery, Orthopedics and Radiology of Small Animal Clinic, University of Veterinary Medicine, Košice, Slovak Republic
Jozef Bodnár ; Private Cytodiagnostic Laboratory, Košice, Slovak Republic
Marián Hluchý ; Department of Surgery, Orthopedics and Radiology of Small Animal Clinic, University of Veterinary Medicine, Košice, Slovak Republic
Slavomír Horňák ; Department of Surgery, Orthopedics and Radiology of Small Animal Clinic, University of Veterinary Medicine, Košice, Slovak Republic
Michael Ushmirsky ; Department of Surgery, Orthopedics and Radiology of Small Animal Clinic, University of Veterinary Medicine, Košice, Slovak Republic
Katarína Ledecká ; Buzulucká 16, Košice, Slovak Republic
Lenka Skurková ; Department of Surgery, Orthopedics and Radiology of Small Animal Clinic, University of Veterinary Medicine, Košice, Slovak Republic

Sažetak

Sheep were used as a model for the examination of radiological and histological changes in bone tissue following total hip replacement. A unilateral total hip replacement procedure was carried out in sheep with radiological examinations at 1, 3 and 6 months after surgery. After six moths, the sheep were euthanized and the bone tissue was collected for histology. The histological examination was focused on superfifi cial reactive changes, bone reactive changes and type and numbers of the cells present. Radiological examination showed no pathological changes. Histological examination revealed new bone formation and remodelling in all samples, three of them (12.5%) exhibiting changes in resorption and new bone formation at the osteoid level. Cellular reaction involving the presence of reactive cells was minimal in all samples (macrophages, fifi broblasts). Changes characteristic of the development of completely mature bone with evident bone structures, including the Hawers system, were observed in eleven samples (45.83%). Disturbances of intactness of the cement coat resulted in cellular activity and aseptic loosening. In our case, cellular activity was minimal and some samples allowed us to observe signs of mature bones which indicated strong fifi xation of endoprosthesis in the bone tissue and alterations at cellular level ongoing even at sixth months following the total hip replacement.

Ključne riječi

aseptic loosening; histology; total hip replacement; sheep

Hrčak ID:

58449

URI

https://hrcak.srce.hr/58449

Datum izdavanja:

16.6.2010.

Podaci na drugim jezicima: hrvatski

Posjeta: 1.136 *