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Differential Pulse Polarographic Studies of Risperidone in Pharmaceutical Formulations

Christine Jeyaseelan
Ravin Jugade
Arun P. Joshi

Puni tekst: engleski, pdf (77 KB) str. 541-544 preuzimanja: 1.027* citiraj
APA 6th Edition
Jeyaseelan, C., Jugade, R. i Joshi, A.P. (2006). Differential Pulse Polarographic Studies of Risperidone in Pharmaceutical Formulations. Croatica Chemica Acta, 79 (4), 541-544. Preuzeto s https://hrcak.srce.hr/5760
MLA 8th Edition
Jeyaseelan, Christine, et al. "Differential Pulse Polarographic Studies of Risperidone in Pharmaceutical Formulations." Croatica Chemica Acta, vol. 79, br. 4, 2006, str. 541-544. https://hrcak.srce.hr/5760. Citirano 14.12.2019.
Chicago 17th Edition
Jeyaseelan, Christine, Ravin Jugade i Arun P. Joshi. "Differential Pulse Polarographic Studies of Risperidone in Pharmaceutical Formulations." Croatica Chemica Acta 79, br. 4 (2006): 541-544. https://hrcak.srce.hr/5760
Harvard
Jeyaseelan, C., Jugade, R., i Joshi, A.P. (2006). 'Differential Pulse Polarographic Studies of Risperidone in Pharmaceutical Formulations', Croatica Chemica Acta, 79(4), str. 541-544. Preuzeto s: https://hrcak.srce.hr/5760 (Datum pristupa: 14.12.2019.)
Vancouver
Jeyaseelan C, Jugade R, Joshi AP. Differential Pulse Polarographic Studies of Risperidone in Pharmaceutical Formulations. Croatica Chemica Acta [Internet]. 2006 [pristupljeno 14.12.2019.];79(4):541-544. Dostupno na: https://hrcak.srce.hr/5760
IEEE
C. Jeyaseelan, R. Jugade i A.P. Joshi, "Differential Pulse Polarographic Studies of Risperidone in Pharmaceutical Formulations", Croatica Chemica Acta, vol.79, br. 4, str. 541-544, 2006. [Online]. Dostupno na: https://hrcak.srce.hr/5760. [Citirano: 14.12.2019.]

Sažetak
A simple and rapid differential pulse polarographic method has been developed for trace determination of risperidone. A well-defined single peak with Ep value of –1.54 V is obtained in Britton-Robinson buffer (pH = 8.0). The linearity is valid up to 5 ´ 10–5 mol/L (r = 0.9995) with minimum detection limit of 2 ´ 10–7 mol/L. Precision of the method developed is implied from the values of the relative mean deviation, standard deviation and coefficient of variation, which are 2.4 %, 0.016 % and 3.2 %, respectively. Commercial formulations of risperidone were analyzed by calibration and standard addition methods. Recovery experiments were found to be quantitative and the determined mass per tablet was obtained within ± 0.2 % of the expected value. The studies have shown that the method is simple, reproducible and accurate and can be used in the analysis of commercial formulations.

Ključne riječi
differential pulse polarography; risperidone

Hrčak ID: 5760

URI
https://hrcak.srce.hr/5760

Posjeta: 1.303 *