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The Changes of Bone-Specific Alkaline Phosphatase (BsALP)Associated With Callus Formation and Rate of Bone Healing

Ante Muljačić ; University Hospital of Traumatology Zagreb, Draškovićeva 19, 10000 Zagreb, Croatia
Renata Poljak-Guberina ; School of Dental Medicine, University of Zagreb, Gundulićeva 5, 10000 Zagreb, Croatia
Josip Turčić ; University Hospital Center Zagreb, Kišpatićeva 12, 10000 Zagreb
Ognjen Živković ; Institute for Rehabilitation and Orthopaedic Aids of the Zagreb University Hospital Center, Božidarevićeva 11, 10000 Zagreb, Croatia
Marko Guberina ; School of Dental Medicine, University of Zagreb, Gundulićeva 5, 10000 Zagreb, Croatia
Boris Klaić ; Dental Polyclinic Zagreb, Perkovčeva 3, 10000 Zagreb, Croatia

Puni tekst: engleski, pdf (1 MB) str. 315-321 preuzimanja: 1.723* citiraj
APA 6th Edition
Muljačić, A., Poljak-Guberina, R., Turčić, J., Živković, O., Guberina, M. i Klaić, B. (2010). The Changes of Bone-Specific Alkaline Phosphatase (BsALP)Associated With Callus Formation and Rate of Bone Healing. Croatica Chemica Acta, 83 (3), 315-321. Preuzeto s https://hrcak.srce.hr/62209
MLA 8th Edition
Muljačić, Ante, et al. "The Changes of Bone-Specific Alkaline Phosphatase (BsALP)Associated With Callus Formation and Rate of Bone Healing." Croatica Chemica Acta, vol. 83, br. 3, 2010, str. 315-321. https://hrcak.srce.hr/62209. Citirano 06.03.2021.
Chicago 17th Edition
Muljačić, Ante, Renata Poljak-Guberina, Josip Turčić, Ognjen Živković, Marko Guberina i Boris Klaić. "The Changes of Bone-Specific Alkaline Phosphatase (BsALP)Associated With Callus Formation and Rate of Bone Healing." Croatica Chemica Acta 83, br. 3 (2010): 315-321. https://hrcak.srce.hr/62209
Harvard
Muljačić, A., et al. (2010). 'The Changes of Bone-Specific Alkaline Phosphatase (BsALP)Associated With Callus Formation and Rate of Bone Healing', Croatica Chemica Acta, 83(3), str. 315-321. Preuzeto s: https://hrcak.srce.hr/62209 (Datum pristupa: 06.03.2021.)
Vancouver
Muljačić A, Poljak-Guberina R, Turčić J, Živković O, Guberina M, Klaić B. The Changes of Bone-Specific Alkaline Phosphatase (BsALP)Associated With Callus Formation and Rate of Bone Healing. Croatica Chemica Acta [Internet]. 2010 [pristupljeno 06.03.2021.];83(3):315-321. Dostupno na: https://hrcak.srce.hr/62209
IEEE
A. Muljačić, R. Poljak-Guberina, J. Turčić, O. Živković, M. Guberina i B. Klaić, "The Changes of Bone-Specific Alkaline Phosphatase (BsALP)Associated With Callus Formation and Rate of Bone Healing", Croatica Chemica Acta, vol.83, br. 3, str. 315-321, 2010. [Online]. Dostupno na: https://hrcak.srce.hr/62209. [Citirano: 06.03.2021.]

Sažetak
The aim of this study was to examine whether the volume of bone-specific alkaline phosphatase
(BsALP) as a biochemical parameter in the early posttraumatic phase may indicate the speed of fracture
healing. The evaluation of the bone healing process has been based on the patient's subjective statement
and radiographic findings. The activity of bone-specific alkaline phosphatase has been measured in the
sera of 41 patients who have been diagnosed with fractures of long bones. All the patients have been
surgically treated. The activity of BsALP was measured on each seventh day during a four-week period.
On the same patients the radiologically follow-up tests have been made during a period of seven months.
Our research has shown that the increase of alkaline phosphatase correlates with an increase of BsALP
levels. The volume of callus correlates with the level of ALP and BsALP. The result leads us to a conclusion
that by monitoring the changes of biochemical parameters: alkaline phosphatase and bone-specific
alcaline phosphatase, we can be able to predict the dynamics of the bone healing.

Ključne riječi
Prognostic Significance; BsALP; Long Bone Fractures

Hrčak ID: 62209

URI
https://hrcak.srce.hr/62209

Posjeta: 2.013 *