hrcak mascot   Srce   HID

Izvorni znanstveni članak

Expression of Matrix Metalloproteinase-1 in Uterosacral Ligaments Tissue of Women with Genital Prolapse

Marko Vulić
Tomislav Strinić
Damir Buković
Snježana Tomić
Tomislav Župić
Mato Pavić
Petra Turčić
Slobodan Mihaljević

Puni tekst: engleski, pdf (54 KB) str. 1411-1417 preuzimanja: 179* citiraj
APA 6th Edition
Vulić, M., Strinić, T., Buković, D., Tomić, S., Župić, T., Pavić, M., ... Mihaljević, S. (2010). Expression of Matrix Metalloproteinase-1 in Uterosacral Ligaments Tissue of Women with Genital Prolapse. Collegium antropologicum, 34 (4), 1411-1417. Preuzeto s https://hrcak.srce.hr/62845
MLA 8th Edition
Vulić, Marko, et al. "Expression of Matrix Metalloproteinase-1 in Uterosacral Ligaments Tissue of Women with Genital Prolapse." Collegium antropologicum, vol. 34, br. 4, 2010, str. 1411-1417. https://hrcak.srce.hr/62845. Citirano 14.11.2019.
Chicago 17th Edition
Vulić, Marko, Tomislav Strinić, Damir Buković, Snježana Tomić, Tomislav Župić, Mato Pavić, Petra Turčić i Slobodan Mihaljević. "Expression of Matrix Metalloproteinase-1 in Uterosacral Ligaments Tissue of Women with Genital Prolapse." Collegium antropologicum 34, br. 4 (2010): 1411-1417. https://hrcak.srce.hr/62845
Harvard
Vulić, M., et al. (2010). 'Expression of Matrix Metalloproteinase-1 in Uterosacral Ligaments Tissue of Women with Genital Prolapse', Collegium antropologicum, 34(4), str. 1411-1417. Preuzeto s: https://hrcak.srce.hr/62845 (Datum pristupa: 14.11.2019.)
Vancouver
Vulić M, Strinić T, Buković D, Tomić S, Župić T, Pavić M i sur. Expression of Matrix Metalloproteinase-1 in Uterosacral Ligaments Tissue of Women with Genital Prolapse. Collegium antropologicum [Internet]. 2010 [pristupljeno 14.11.2019.];34(4):1411-1417. Dostupno na: https://hrcak.srce.hr/62845
IEEE
M. Vulić, et al., "Expression of Matrix Metalloproteinase-1 in Uterosacral Ligaments Tissue of Women with Genital Prolapse", Collegium antropologicum, vol.34, br. 4, str. 1411-1417, 2010. [Online]. Dostupno na: https://hrcak.srce.hr/62845. [Citirano: 14.11.2019.]

Sažetak
Collagen metabolism is altered in the pelvic organ tissues of women with genital prolapse. The aim of this study was to compare collagen metabolism by measuring matrix metalloproteinase – 1 (MMP – 1) expression in uterosacral ligament tissues of postmenopausal women with and without genital prolapse. Uterosacral ligament tissues were obtained at the time of abdominal or vaginal surgery from twenty-four patients with pelvic organ prolapse (POP) and 21 women who underwent gynecologic surgery for benign indications. The tissue samples were analyzed by immunohistochemistry. There were no differences in age, BMI and parity between two groups. The patients with genital prolapse demonstrated significantly higher occurences of MMP – 1 expression compared to controls. These findings indicate that increased MMP – 1 expression in uterosacral ligaments is associated with genital prolapse. Our data are consistent with the theory that increased collagen breakdown may play an important role in the onset and development of pelvic organ prolapse (POP).

Ključne riječi
MMP – 1; uterosacral ligament; genital prolapse

Hrčak ID: 62845

URI
https://hrcak.srce.hr/62845

Posjeta: 333 *