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Preliminary communication

Differential Diagnostic Relevance of High Resolution Magnetic Resonance in Patients with Possible Multiple System Atrophy (MSA) – A Case Report

Koraljka Bačić Baronica
Goran Ivkić
David Ozretić
Goran Miličević

Fulltext: english, pdf (161 KB) pages 287-292 downloads: 244* cite
APA 6th Edition
Bačić Baronica, K., Ivkić, G., Ozretić, D. & Miličević, G. (2011). Differential Diagnostic Relevance of High Resolution Magnetic Resonance in Patients with Possible Multiple System Atrophy (MSA) – A Case Report. Collegium antropologicum, 35 supplement 1 (1), 287-292. Retrieved from https://hrcak.srce.hr/64094
MLA 8th Edition
Bačić Baronica, Koraljka, et al. "Differential Diagnostic Relevance of High Resolution Magnetic Resonance in Patients with Possible Multiple System Atrophy (MSA) – A Case Report." Collegium antropologicum, vol. 35 supplement 1, no. 1, 2011, pp. 287-292. https://hrcak.srce.hr/64094. Accessed 28 May 2020.
Chicago 17th Edition
Bačić Baronica, Koraljka, Goran Ivkić, David Ozretić and Goran Miličević. "Differential Diagnostic Relevance of High Resolution Magnetic Resonance in Patients with Possible Multiple System Atrophy (MSA) – A Case Report." Collegium antropologicum 35 supplement 1, no. 1 (2011): 287-292. https://hrcak.srce.hr/64094
Harvard
Bačić Baronica, K., et al. (2011). 'Differential Diagnostic Relevance of High Resolution Magnetic Resonance in Patients with Possible Multiple System Atrophy (MSA) – A Case Report', Collegium antropologicum, 35 supplement 1(1), pp. 287-292. Available at: https://hrcak.srce.hr/64094 (Accessed 28 May 2020)
Vancouver
Bačić Baronica K, Ivkić G, Ozretić D, Miličević G. Differential Diagnostic Relevance of High Resolution Magnetic Resonance in Patients with Possible Multiple System Atrophy (MSA) – A Case Report. Collegium antropologicum [Internet]. 2011 [cited 2020 May 28];35 supplement 1(1):287-292. Available from: https://hrcak.srce.hr/64094
IEEE
K. Bačić Baronica, G. Ivkić, D. Ozretić and G. Miličević, "Differential Diagnostic Relevance of High Resolution Magnetic Resonance in Patients with Possible Multiple System Atrophy (MSA) – A Case Report", Collegium antropologicum, vol.35 supplement 1, no. 1, pp. 287-292, 2011. [Online]. Available: https://hrcak.srce.hr/64094. [Accessed: 28 May 2020]

Abstracts
Multiple system atrophy (MSA) is sporadic, progressive neurodegenerative disorder characterized clinically by autonomic dysfunction, Parkinsonism (MSA-P), and cerebellar ataxia (MSA-C) in any combination. Parkinsonism is present in the majority of patients (80%). Early in the course of the disease autonomic dysfunctions are present in approximately 40% of patients, while the domination of cerebellar symptoms is present in 20% of all patients1,2. According to second consensus statement on diagnosis of MSA, to make the diagnosis of possible MSA, except Parkinsonism or a cerebellar syndrome, there must be one feature involving autonomic dysfunction plus one other additional that can include findings on
history, clinical examination or changes in structural or functional imaging3. We present a case of 60-year old male with Parkinsonism and cerebellar symptoms accompanied with signs of autonomic nervous system involvment. Level of autonomic dysfunction was not the level required for the diagnosis of probable MSA. On initially performed 1.5T MRI, the most prominent neurodegenerative feature of brain stem, cerebellum and basal ganglia was atrophy, however features like »hot-cross bun« sign, »slit-like« putaminal rim and middle cerebellar peduncle hyperintensities were detected only after MR imaging on higher resolution (3T) device4. Our case points to the possibility that some typical structural changes that can help in diagnostic process may not be clearly visible on 1.5 T MRI devices. In such cases we suggest using 3T MRI device, if feasible, in order to demonstrate findings that may help in establishing the diagnosis of possible MSA.

Keywords
multiple system atrophy; magnetic resonance imaging; diagnosis

Hrčak ID: 64094

URI
https://hrcak.srce.hr/64094

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