hrcak mascot   Srce   HID

Pregledni rad
https://doi.org/10.2478/10004-1254-62-2011-2052

Chemical Methods for Determination of Hydroxylated Metabolites of Polycyclic Aromatic Hydrocarbons and Polychlorinated Biphenyls in Biological Material

Darija Klinčić ; Institut za medicinska istraživanja i medicinu rada, Zagreb, Hrvatska
Snježana Herceg Romanić ; Institut za medicinska istraživanja i medicinu rada, Zagreb, Hrvatska

Puni tekst: hrvatski, pdf (120 KB) str. 77-88 preuzimanja: 1.493* citiraj
APA 6th Edition
Klinčić, D. i Herceg Romanić, S. (2011). Kemijske metode određivanja hidroksiliranih metabolita policikličkih aromatskih ugljikovodika i poliklorbifenila u biološkome materijalu. Arhiv za higijenu rada i toksikologiju, 62 (1), 77-88. https://doi.org/10.2478/10004-1254-62-2011-2052
MLA 8th Edition
Klinčić, Darija i Snježana Herceg Romanić. "Kemijske metode određivanja hidroksiliranih metabolita policikličkih aromatskih ugljikovodika i poliklorbifenila u biološkome materijalu." Arhiv za higijenu rada i toksikologiju, vol. 62, br. 1, 2011, str. 77-88. https://doi.org/10.2478/10004-1254-62-2011-2052. Citirano 25.02.2021.
Chicago 17th Edition
Klinčić, Darija i Snježana Herceg Romanić. "Kemijske metode određivanja hidroksiliranih metabolita policikličkih aromatskih ugljikovodika i poliklorbifenila u biološkome materijalu." Arhiv za higijenu rada i toksikologiju 62, br. 1 (2011): 77-88. https://doi.org/10.2478/10004-1254-62-2011-2052
Harvard
Klinčić, D., i Herceg Romanić, S. (2011). 'Kemijske metode određivanja hidroksiliranih metabolita policikličkih aromatskih ugljikovodika i poliklorbifenila u biološkome materijalu', Arhiv za higijenu rada i toksikologiju, 62(1), str. 77-88. https://doi.org/10.2478/10004-1254-62-2011-2052
Vancouver
Klinčić D, Herceg Romanić S. Kemijske metode određivanja hidroksiliranih metabolita policikličkih aromatskih ugljikovodika i poliklorbifenila u biološkome materijalu. Arh Hig Rada Toksikol. [Internet]. 2011 [pristupljeno 25.02.2021.];62(1):77-88. https://doi.org/10.2478/10004-1254-62-2011-2052
IEEE
D. Klinčić i S. Herceg Romanić, "Kemijske metode određivanja hidroksiliranih metabolita policikličkih aromatskih ugljikovodika i poliklorbifenila u biološkome materijalu", Arhiv za higijenu rada i toksikologiju, vol.62, br. 1, str. 77-88, 2011. [Online]. https://doi.org/10.2478/10004-1254-62-2011-2052

Sažetak
This review presents methods for the analysis of hydroxylated metabolites of polycyclic aromatic hydrocarbons and polychlorinated biphenyls in humans and animals. These metabolites serve as biomarkers of human and animal exposure to the mentioned pollutants, but some metabolites also have toxic properties.
Most are analysed in urine, which is the most accessible sample, but they can also be analysed in human and animal liver, bile, and adipose tissue. Their analysis is important for assessing bioavailability of aromatic pollutants and their toxicity in human
organism, but also the toxicity of metabolites themselves. Advancements in analytical methods have made it possible to analyse multiple metabolites in a sample at the same time. New extraction techniques and more precise and selective qualitative and quantitative analyses can now detect very low metabolite oncentrations. An extra advantage is that these simple techniques require less chemicals and time.

Ključne riječi
analytical procedures; biomarkers; metabolism; PAH; PCB; pollutants; toxicity

Hrčak ID: 65317

URI
https://hrcak.srce.hr/65317

[hrvatski]

Posjeta: 1.913 *